[HTML][HTML] MITF in normal melanocytes, cutaneous and uveal melanoma: a delicate balance

MC Gelmi, LE Houtzagers, T Strub, I Krossa… - International journal of …, 2022 - mdpi.com
Microphthalmia-associated transcription factor (MITF) is an important regulator of
melanogenesis and melanocyte development. Although it has been studied extensively in …

Prognostic biomarkers in uveal melanoma: The status quo, recent advances and future directions

NJ Lamas, A Martel, S Nahon-Estève, S Goffinet… - Cancers, 2021 - mdpi.com
Simple Summary Although rare, uveal melanoma (UM) is the most common cancer that
develops inside adult eyes. The prognosis is poor, since 50% of patients will develop lethal …

[HTML][HTML] Loss of BAP1 is associated with upregulation of the NFkB pathway and increased HLA class I expression in uveal melanoma

Z Souri, APA Wierenga, C van Weeghel… - Cancers, 2019 - mdpi.com
One of the characteristics of prognostically infaust uveal melanoma (UM) is an inflammatory
phenotype, which is characterized by high numbers of infiltrating T cells and macrophages …

TAP1, a potential immune-related prognosis biomarker with functional significance in uveal melanoma

R Zhu, YT Chen, BW Wang, YY You, XH Wang, HT **e… - BMC cancer, 2023 - Springer
Background TAP1 is an immunomodulation-related protein that plays different roles in
various malignancies. This study investigated the transcriptional expression profile of TAP1 …

[HTML][HTML] Novel prognostic immunohistochemical markers in uveal melanoma-literature review

M Gajdzis, R Kaczmarek, P Gajdzis - Cancers, 2021 - mdpi.com
Simple Summary The following study provides an overview of the English-language
literature on the search for new prognostic factors for uveal melanoma. Uveal melanoma is …

Clinicopathological relevance of NFκB1/p50 nuclear immunoreactivity and its relationship with the inflammatory environment of uveal melanoma

MK Singh, L Singh, K Chosdol, N Pushker… - Experimental and …, 2019 - Elsevier
Purpose To analyze the activation of NFκB1/p50 in the inflammatory and non-inflammatory
environment of uveal melanoma and its association with clinicopathological factors and …

[PDF][PDF] ager, M..(2022)

MC Gelmi, LE Houtzagers… - MITF in normal … - scholarlypublications …
Microphthalmia-associated transcription factor (MITF) is an important regulator of
melanogenesis and melanocyte development. Although it has been studied extensively in …

Understanding the function of NF-κB transcription factor c-Rel in pancreatic cancer

D Kabacaoglu - 2021 - mediatum.ub.tum.de
Here in this work, we analyzed the function of c-Rel in pancreatic cancer with the use of
murine pancreatic cancer models. We showed that increase in c-Rel level reduces overall …