[HTML][HTML] Cellular mechanisms of melatonin: insight from neurodegenerative diseases

D Chen, T Zhang, TH Lee - Biomolecules, 2020 - mdpi.com
Neurodegenerative diseases are the second most common cause of death and
characterized by progressive impairments in movement or mental functioning in the central …

Biochemical reactivity of melatonin with reactive oxygen and nitrogen species: a review of the evidence

RJ Reiter, D Tan, LC Manchester, W Qi - Cell biochemistry and biophysics, 2001 - Springer
Abstract Melatonin (N-acetyl-5-methoxytryptamine), an endogenously produced indole
found throughout the animal kingdom, was recently reported, using a variety of techniques …

Assay of total antioxidant capacity: comparison of four methods as applied to human blood plasma

A Janaszewska, G Bartosz - Scandinavian journal of clinical and …, 2002 - Taylor & Francis
Four spectrophotometric methods of determination of antioxidant capacity: a method based
on the scavenging of the 1, 1-diphenyl-2-picrylhydrazyl (DPPH) free radical, the''ferric …

Melatonin in walnuts: influence on levels of melatonin and total antioxidant capacity of blood

RJ Reiter, LC Manchester, D Tan - Nutrition, 2005 - Elsevier
OBJECTIVE: We investigated whether melatonin is present in walnuts (Juglans regia L.)
and, if so, tested whether eating walnuts influences melatonin levels and the total …

Melatonin in Alzheimer's disease: a latent endogenous regulator of neurogenesis to mitigate Alzheimer's neuropathology

MF Hossain, MS Uddin, GMS Uddin… - Molecular …, 2019 - Springer
Melatonin, a pineal gland synthesized neurohormone is known as a multifunctioning
pleiotropic agent which has a wide range of neuroprotective role in manifold age-related …

Antioxidative effects of melatonin in protection against cellular damage caused by ionizing radiation

M Karbownik, RJ Reiter - Proceedings of the Society for …, 2000 - Wiley Online Library
Ionizing radiation is classified as a potent carcinogen, and its injury to living cells is, to a
large extent, due to oxidative stress. The molecule most often reported to be damaged by …

Melatonin: a novel protective agent against oxidative injury of the ischemic/reperfused heart

RJ Reiter, DX Tan - Cardiovascular research, 2003 - academic.oup.com
This brief review summarizes the recently obtained evidence which illustrates the beneficial
effects of the endogenously produced antioxidant, melatonin, in reducing tissue damage …

On the in vitro antioxidative properties of melatonin

I Gulcin, ME Buyukokuroglu, M Oktay… - Journal of Pineal …, 2002 - Wiley Online Library
The aim of this study is to examine possible in vitro antioxidant effects of melatonin. Thus,
the total in vitro antioxidant activity of melatonin was studied using a thiocyanate method …

Pharmacology and physiology of melatonin in the reduction of oxidative stress in vivo

RJ Reiter, DX Tan, W Qi, LC Manchester, M Karbownik… - Neurosignals, 2000 - karger.com
This brief resume summarizes the evidence which shows that melatonin is a significant free
radical scavenger and antioxidant at both physiological and pharmacological concentrations …

Reactive oxygen and nitrogen species and cellular and organismal decline: amelioration with melatonin

RJ Reiter, D Tan, S Burkhardt - Mechanisms of Ageing and Development, 2002 - Elsevier
Cellular and organismal decline is, in part, believed to be a consequence of oxygen and
nitrogen-based reactants which persistently damage macromolecules throughout a lifetime …