KNOX genes: versatile regulators of plant development and diversity
Knotted1-like homeobox (KNOX) proteins are homeodomain transcription factors that
maintain an important pluripotent cell population called the shoot apical meristem, which …
maintain an important pluripotent cell population called the shoot apical meristem, which …
Deregulated homeobox gene expression in cancer: cause or consequence?
C Abate-Shen - Nature Reviews Cancer, 2002 - nature.com
Homeobox genes comprise a large and essential family of developmental regulators that
are vital for all aspects of growth and differentiation. Although many studies have reported …
are vital for all aspects of growth and differentiation. Although many studies have reported …
Low affinity binding site clusters confer hox specificity and regulatory robustness
In animals, Hox transcription factors define regional identity in distinct anatomical domains.
How Hox genes encode this specificity is a paradox, because different Hox proteins bind …
How Hox genes encode this specificity is a paradox, because different Hox proteins bind …
MicroRNA Targets in Drosophila
The recent discoveries of microRNAs (miRNAs) and characterization of the first few targets
of their gene products in Caenorhabditis elegans and Drosophila melanogaster have set the …
of their gene products in Caenorhabditis elegans and Drosophila melanogaster have set the …
[HTML][HTML] Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins
Members of transcription factor families typically have similar DNA binding specificities yet
execute unique functions in vivo. Transcription factors often bind DNA as multiprotein …
execute unique functions in vivo. Transcription factors often bind DNA as multiprotein …
[HTML][HTML] Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b
E Kroon, J Krosl, U Thorsteinsdottir, S Baban… - The EMBO …, 1998 - embopress.org
Abstract Hoxa9, Meis1 and Pbx1 encode homeodomaincontaining proteins implicated in
leukemic transformation in both mice and humans. Hoxa9, Meis1 and Pbx1 proteins have …
leukemic transformation in both mice and humans. Hoxa9, Meis1 and Pbx1 proteins have …
The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes
AC Spradling, D Stern, A Beaton, EJ Rhem, T Laverty… - Genetics, 1999 - academic.oup.com
A fundamental goal of genetics and functional genomics is to identify and mutate every gene
in model organisms such as Drosophila melanogaster. The Berkeley Drosophila Genome …
in model organisms such as Drosophila melanogaster. The Berkeley Drosophila Genome …
[HTML][HTML] Hox cofactors in vertebrate development
CB Moens, L Selleri - Developmental biology, 2006 - Elsevier
Hox genes encode homeodomain-containing transcription factors that pattern the body axes
of animal embryos. It is well established that the exquisite DNA-binding specificity that …
of animal embryos. It is well established that the exquisite DNA-binding specificity that …
The transcriptional diversity of 25 Drosophila cell lines
Drosophila melanogaster cell lines are important resources for cell biologists. Here, we
catalog the expression of exons, genes, and unannotated transcriptional signals for 25 lines …
catalog the expression of exons, genes, and unannotated transcriptional signals for 25 lines …
Hox proteins meet more partners
The Hox genes are clustered sets of homeobox-containing genes that play a central role in
animal development. Recent genetic and molecular data suggest that Hox proteins interact …
animal development. Recent genetic and molecular data suggest that Hox proteins interact …