Small molecules in the treatment of COVID-19

S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2

K Gao, R Wang, J Chen, L Cheng, J Frishcosy… - Chemical …, 2022 - ACS Publications
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …

Ongoing and potential novel trends of pomegranate fruit peel; a comprehensive review of its health benefits and future perspectives as nutraceutical

HA Fahmy, MA Farag - Journal of Food Biochemistry, 2022 - Wiley Online Library
Pomegranate is an ancient shrub, globally distributed nowadays. It has been used in the
middle east as a medicinal food and traditional medicine for thousands of years …

Metabolites profiling and cheminformatics bioprospection of selected medicinal plants against the main protease and RNA-dependent RNA polymerase of SARS-CoV …

AA Lanrewaju, AM Enitan-Folami… - Journal of …, 2024 - Taylor & Francis
Despite the existence of some vaccines, SARS-CoV-2 (S-2) infections persist for various
reasons relating to vaccine reluctance, rapid mutation rate, and an absence of specific …

Herbal formulations in fighting against the SARS-CoV-2 infection

JD Abidharini, BR Souparnika, J Elizabeth… - … and Drug Discovery for …, 2023 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a serious
global pandemic from the year 2019. Many allopathic and prevention measures have been …

Virtual screening and molecular dynamics studies of novel small molecules targeting Schistosoma mansoni DHODH: identification of potential inhibitors

SC Ja'afaru, A Uzairu, VK Mishra, MS Sallau… - In Silico …, 2024 - Springer
Schistosomiasis affects more than 200 million individuals globally, mainly in underprivileged
areas, leading to long-term health issues and adding to socio-economic challenges. The …

Computational modeling and molecular dynamics studies of methyl sulfonyl acetate derivatives as potent SmTGR inhibitors: insights into binding interactions

SC Ja'afaru, A Uzairu, VK Mishra, MS Sallau… - Molecular …, 2024 - Taylor & Francis
Schistosomiasis, a neglected tropical disease caused by flatworms of the Schistosoma
genus, can lead to severe health complications such as Hepatosplenomegaly, intestinal …

In‐Silico Screening, Molecular Dynamics, and DFT Analysis of ZINC and ChEMBL Library Compounds for SARS‐CoV‐2 Main Protease Inhibition

S Verma, A Dubey, R Singh, R Tayade… - …, 2025 - Wiley Online Library
Although COVID‐19 is no longer classified as a global emergency, the emergence of SARS‐
CoV‐2 variants highlights the urgent need for antiviral drug discovery. This study identifies …

Polyphenols in Control of COVID‐19

E Berdimurodov, K Berdimuradov… - … and Engineering of …, 2024 - Wiley Online Library
Polyphenols are a diverse group of naturally occurring compounds in various plant‐based
foods with potential antiviral and anti‐inflammatory properties. This chapter discusses the …

Predicting global diet-disease relationships at the atomic level: a COVID-19 case study

LKY Cheung, RY Yada - Current Opinion in Food Science, 2022 - Elsevier
Highlights•Molecular docking may help reveal atomic-level basis for epidemiological
trends.•Emerging pandemics such as COVID-19 has led to unprecedented in silico food …