Release of small bioactive molecules from physical gels

J Mayr, C Saldías, DD Díaz - Chemical Society Reviews, 2018 - pubs.rsc.org
Pharmaceutical drugs with low water solubility have always received great attention within
the scientific community. The reduced bioavailability and the need of frequent …

[HTML][HTML] From supramolecular hydrogels to multifunctional carriers for biologically active substances

J Skopinska-Wisniewska, S De la Flor… - International Journal of …, 2021 - mdpi.com
Supramolecular hydrogels are 3D, elastic, water-swelled materials that are held together by
reversible, non-covalent interactions, such as hydrogen bonds, hydrophobic, ionic, host …

Beyond covalent crosslinks: applications of supramolecular gels

T Christoff-Tempesta, AJ Lew, JH Ortony - Gels, 2018 - mdpi.com
Traditionally, gels have been defined by their covalently cross-linked polymer networks.
Supramolecular gels challenge this framework by relying on non-covalent interactions for …

Recent updates on supramolecular‐based drug delivery–macrocycles and supramolecular gels

VS Saji - The Chemical Record, 2022 - Wiley Online Library
Supramolecules‐based drug delivery has attracted significant recent research attention as it
could enhance drug solubility, retention time, targeting, and stimuli responsiveness. Among …

Spatially-resolved soft materials for controlled release–hybrid hydrogels combining a robust photo-activated polymer gel with an interactive supramolecular gel

PRA Chivers, DK Smith - Chemical Science, 2017 - pubs.rsc.org
Hybrid hydrogels based on self-assembling low-molecular-weight gelator (LMWG) DBS-
CONHNH2 (DBS= 1, 3; 2, 4-dibenzylidene-D-sorbitol) and crosslinked polymer gelator (PG) …

Formulation, in-vitro and in-vivo pharmacokinetic evaluation of simvastatin nanostructured lipid carrier loaded transdermal drug delivery system

S Brito Raj, KB Chandrasekhar, KB Reddy - Future Journal of …, 2019 - Springer
Background A simvastatin nanostructured lipid carrier loaded transdermal patch was
developed to enhance the bioavailability and therapeutic effect. Methods Simvastatin NLC …

In Vitro Drug Dissolution/Permeation Testing of Nanocarriers for Skin Application: a Comprehensive Review

R Sheshala, NK Anuar, NH Abu Samah, TW Wong - AAPS PharmSciTech, 2019 - Springer
This review highlights in vitro drug dissolution/permeation methods available for topical and
transdermal nanocarriers that have been designed to modulate the propensity of drug …

[HTML][HTML] Mixed Micellar Gel of Poloxamer Mixture for Improved Solubilization of Poorly Water-Soluble Ibuprofen and Use as Thermosensitive In Situ Gel

N Hirun, P Kraisit, S Santhan - Pharmaceutics, 2024 - mdpi.com
The aqueous solution of binary mixtures of amphiphilic copolymers is a potential platform for
fabricating mixed polymeric micelles for pharmaceutical applications, particularly in …

[HTML][HTML] Topical mucoadhesive alginate-based hydrogel loading ketorolac for pain management after pharmacotherapy, ablation, or surgical removal in condyloma …

S El Moussaoui, F Fernández-Campos, C Alonso… - Gels, 2021 - mdpi.com
Condyloma acuminata is an infectious disease caused by the human papilloma virus (HPV)
and one of the most common sexually transmitted infections. It is manifested as warts that …

Nanostructured lipid carriers loaded with Halobetasol propionate for topical treatment of inflammation: Development, characterization, biopharmaceutical behavior …

P Carvajal-Vidal, R González-Pizarro, C Araya… - International Journal of …, 2020 - Elsevier
The aim of this research was the development and characterization of three gel dosage
forms of Halobetasol propionate loaded lipid nanoparticles (HB-NLC) for the treatment of …