Stress often affects our social lives. When undergoing high-level or persistent stress,
individuals frequently retract from social interactions and become irritable and hostile …

Early life stress is a well-documented risk factor for the development of psychopathology in
genetically predisposed individuals. As it is hard to study how early life stress impacts …

Depression is a debilitating mental disease affecting a large population worldwide, the
pathophysiological mechanisms of which remain incompletely understood. Prenatal …

Childhood stress and trauma are associated with substance use disorders in adulthood, but
the neurological changes that confer increased vulnerability are largely unknown. In this …

Adverse early life experience decreases adult hippocampal neurogenesis and results in
increased vulnerability to neuropsychiatric disorders. Despite that the effects of postnatal …

Individuals with mood disorders or with addiction, impulsivity and some personality
disorders can share in common a dysfunction in how the brain perceives reward, where …

The aim of this review is to highlight our knowledge of the various drugs of abuse that can
prove potential teratogens affecting the brain and cognitive development in an individual …

Exposure to stressors elicits a spectrum of responses that span from potentially adaptive to
maladaptive consequences at the structural, cellular and physiological level. These …

Early life stress (ELS) increases the risk for later cognitive and emotional dysfunction, and
has been implicated in the etiology of multiple psychiatric disorders. We hypothesize that …

Nicotinic acetylcholine receptors (nAChR s) affect multiple physiological functions in the
brain and their functions are modulated by regulatory proteins of the Lynx family. Here, we …