Nanomedicine combats drug resistance in lung cancer
Lung cancer is the second most prevalent cancer and the leading cause of cancer‐related
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …
[HTML][HTML] Micro and nano-carriers-based pulmonary drug delivery system: Their current updates, challenges, and limitations–A review
The lung is an attractive target for drug delivery because of the ease of non-invasive
administration via inhalation, bypassing metabolism in the liver, direct delivery to the …
administration via inhalation, bypassing metabolism in the liver, direct delivery to the …
A critical review on developments in drying technologies for enhanced stability and bioavailability of pharmaceuticals
Drying is a widely adopted unit operation that enhances the stability of pharmaceuticals.
Conventionally, freeze-drying has been chosen, as evidenced by the numerous freeze-dried …
Conventionally, freeze-drying has been chosen, as evidenced by the numerous freeze-dried …
Clofazimine nanoclusters show high efficacy in experimental TB with amelioration in paradoxical lung inflammation
The rise of tuberculosis (TB) superbugs has impeded efforts to control this infectious ailment,
and new treatment options are few. Paradoxical Inflammation (PI) is another major problem …
and new treatment options are few. Paradoxical Inflammation (PI) is another major problem …
[HTML][HTML] Advancements in chitosan-based nanoparticles for pulmonary drug delivery
TM Zacaron, MLS Silva, MP Costa, DM Silva, AC Silva… - Polymers, 2023 - mdpi.com
The evolution of respiratory diseases represents a considerable public health challenge, as
they are among the leading causes of death worldwide. In this sense, in addition to the high …
they are among the leading causes of death worldwide. In this sense, in addition to the high …
Effective cerebral tuberculosis treatment via nose-to-brain transport of anti-TB drugs using mucoadhesive nano-aggregates
Central nervous system tuberculosis (CNS-TB) is a severe form of extra-pulmonary
tuberculosis with high mortality and morbidity rates. The standard treatment regimen for CNS …
tuberculosis with high mortality and morbidity rates. The standard treatment regimen for CNS …
Trans-nasal brain delivery of anti-TB drugs by methyl-β-cyclodextrin microparticles show efficient mycobacterial clearance from central nervous system
Central nervous system tuberculosis (CNS-TB) is the most severe extra-pulmonary
manifestation of tuberculosis (TB), facing significant challenges due to the limited …
manifestation of tuberculosis (TB), facing significant challenges due to the limited …
Breaking the Cycle: Matrix Metalloproteinase Inhibitors as an Alternative Approach in Managing Tuberculosis Pathogenesis and Progression
Mycobacterium tuberculosis (Mtb) has long posed a significant challenge to global public
health, resulting in approximately 1.6 million deaths annually. Pulmonary tuberculosis (TB) …
health, resulting in approximately 1.6 million deaths annually. Pulmonary tuberculosis (TB) …
Inhalable chitosan-coated nano-assemblies potentiate niclosamide for targeted abrogation of non-small-cell lung cancer through dual modulation of autophagy and …
Lung carcinoma, particularly non-small-cell lung cancer (NSCLC), accounts for a significant
portion of cancer-related deaths, with a fatality rate of approximately 19%. Niclosamide …
portion of cancer-related deaths, with a fatality rate of approximately 19%. Niclosamide …
Targeted delivery of the metastasis-specific tumour homing TMTP1 peptide to non-small-cell lung cancer (NSCLC) using inhalable hybrid nano-assemblies
Lung cancer is one of the most fatal malignancies, with the highest death rate (∼ 19%), and
the NSCLC type accounts for∼ 85% of lung cancers. In the search for new treatments …
the NSCLC type accounts for∼ 85% of lung cancers. In the search for new treatments …