Inflammation in obesity, diabetes, and related disorders
Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …
Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
J Guo, X Huang, L Dou, M Yan, T Shen… - Signal Transduction and …, 2022 - nature.com
Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …
tissue and cell functions and significant increases in the risks of various aging-related …
[HTML][HTML] The role of inflammation in diabetes: current concepts and future perspectives
S Tsalamandris, AS Antonopoulos… - European cardiology …, 2019 - ncbi.nlm.nih.gov
Diabetes is a complex metabolic disorder affecting the glucose status of the human body.
Chronic hyperglycaemia related to diabetes is associated with end organ failure. The clinical …
Chronic hyperglycaemia related to diabetes is associated with end organ failure. The clinical …
Muscle–organ crosstalk: the emerging roles of myokines
MCK Severinsen, BK Pedersen - Endocrine reviews, 2020 - academic.oup.com
Physical activity decreases the risk of a network of diseases, and exercise may be
prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia …
prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia …
Macrophage biology in development, homeostasis and disease
TA Wynn, A Chawla, JW Pollard - Nature, 2013 - nature.com
Macrophages, the most plastic cells of the haematopoietic system, are found in all tissues
and show great functional diversity. They have roles in development, homeostasis, tissue …
and show great functional diversity. They have roles in development, homeostasis, tissue …
Type 2 diabetes as an inflammatory disease
Components of the immune system are altered in obesity and type 2 diabetes (T2D), with the
most apparent changes occurring in adipose tissue, the liver, pancreatic islets, the …
most apparent changes occurring in adipose tissue, the liver, pancreatic islets, the …
Inflammatory mechanisms in obesity
MF Gregor, GS Hotamisligil - Annual review of immunology, 2011 - annualreviews.org
The modern rise in obesity and its strong association with insulin resistance and type 2
diabetes have elicited interest in the underlying mechanisms of these pathologies. The …
diabetes have elicited interest in the underlying mechanisms of these pathologies. The …
[HTML][HTML] Inflammatory links between obesity and metabolic disease
The obesity epidemic has forced us to evaluate the role of inflammation in the health
complications of obesity. This has led to a convergence of the fields of immunology and …
complications of obesity. This has led to a convergence of the fields of immunology and …
Obesity, inflammation, toll-like receptor 4 and fatty acids
Obesity leads to an inflammatory condition that is directly involved in the etiology of
cardiovascular diseases, type 2 diabetes mellitus, and certain types of cancer. The classic …
cardiovascular diseases, type 2 diabetes mellitus, and certain types of cancer. The classic …
Relationship between oxidative stress, ER stress, and inflammation in type 2 diabetes: the battle continues
Type 2 diabetes (T2D) is a metabolic disorder characterized by hyperglycemia and insulin
resistance in which oxidative stress is thought to be a primary cause. Considering that …
resistance in which oxidative stress is thought to be a primary cause. Considering that …