Production of bioactive plant secondary metabolites through in vitro technologies—status and outlook

C Wawrosch, SB Zotchev - Applied Microbiology and Biotechnology, 2021 - Springer
Medicinal plants have been used by mankind since ancient times, and many bioactive plant
secondary metabolites are applied nowadays both directly as drugs, and as raw materials …

Environmental and genetic factors involved in plant protection-associated secondary metabolite biosynthesis pathways

X Zhan, Z Chen, R Chen, C Shen - Frontiers in Plant Science, 2022 - frontiersin.org
Plant specialized metabolites (PSMs) play essential roles in the adaptation to harsh
environments and function in plant defense responses. PSMs act as key components of …

Natural products for cancer therapy: a review of their mechanism of actions and toxicity in the past decade

YO Ali Abdalla, B Subramaniam… - Journal of Tropical …, 2022 - Wiley Online Library
The ethnopharmacological information gathered over many centuries and the presence of
diverse metabolites have made the medicinal plants as the prime source of drugs. Despite …

[HTML][HTML] Medicinal and mechanistic overview of artemisinin in the treatment of human diseases

AM Posadino, R Giordo, G Pintus… - Biomedicine & …, 2023 - Elsevier
Artemisinin (ART) is a bioactive compound isolated from the plant Artemisia annua and has
been traditionally used to treat conditions such as malaria, cancer, viral infections, bacterial …

Exogenous strigolactone (GR24) positively regulates growth, photosynthesis, and improves glandular trichome attributes for enhanced artemisinin production in …

KI Wani, A Zehra, S Choudhary, M Naeem… - Journal of Plant Growth …, 2023 - Springer
Artemisia annua is a medicinal plant particularly known for the production of a
sesquiterpene lactone artemisinin; a specialty metabolite known for its efficacy in the …

Insights into strigolactone (GR24) mediated regulation of cadmium-induced changes and ROS metabolism in Artemisia annua

KI Wani, M Naeem, MMA Khan, T Aftab - Journal of Hazardous Materials, 2023 - Elsevier
Agricultural soil contamination and subsequently crops still require alternative solutions to
reduce associated environmental risks. The effects of strigolactones (SLs) in alleviating …

Metal oxide nanoparticles and plant secondary metabolism: unraveling the game-changer nano-elicitors

M Inam, I Attique, M Zahra, AK Khan, M Hahim… - Plant Cell, Tissue and …, 2023 - Springer
Secondary metabolites (SMs) are biologically active compounds that have a very high
commercial value due to their invaluable medicinal properties. However, the production …

Functions of Representative Terpenoids and Their Biosynthesis Mechanisms in Medicinal Plants

Q Wang, X Zhao, Y Jiang, B **, L Wang - Biomolecules, 2023 - mdpi.com
Terpenoids are the broadest and richest group of chemicals obtained from plants. These
plant-derived terpenoids have been extensively utilized in various industries, including food …

Artemisinins in combating viral infections like SARS-CoV-2, inflammation and cancers and options to meet increased global demand

K Farmanpour-Kalalagh… - Frontiers in Plant …, 2022 - frontiersin.org
Artemisinin is a natural bioactive sesquiterpene lactone containing an unusual
endoperoxide 1, 2, 4-trioxane ring. It is derived from the herbal medicinal plant Artemisia …

From plant to yeast—Advances in biosynthesis of artemisinin

L Zhao, Y Zhu, H Jia, Y Han, X Zheng, M Wang… - Molecules, 2022 - mdpi.com
Malaria is a life-threatening disease. Artemisinin-based combination therapy (ACT) is the
preferred choice for malaria treatment recommended by the World Health Organization. At …