Because germline mutations are the source of all evolutionary adaptations and heritable
diseases, characterizing their properties and the rate at which they arise across individuals …

We hypothesize that heritable epigenetic changes can affect rates of fitness increase as well
as patterns of genotypic and phenotypic change during adaptation. In particular, we suggest …

Mutation is the ultimate source of genetic variation. The most direct and unbiased method of
studying spontaneous mutations is via mutation accumulation (MA) lines. Until recently, MA …

We employed deep genome sequencing of two parents and 12 of their offspring to estimate
the mutation rate per site per generation in a full-sib family of Drosophila melanogaster …

We estimated the spontaneous mutation rate in Heliconius melpomene by genome
sequencing of a pair of parents and 30 of their offspring, based on the ratio of number of de …

Mutation is the ultimate source of all genetic variation, and over the last 10 years the ready
availability of whole-genome sequencing has permitted direct estimation of mutation rate for …

Because spontaneous mutation is the source of all genetic diversity, measuring mutation
rates can reveal how natural selection drives patterns of variation within and between …

Mutations spawn genetic variation which, in turn, fuels evolution. Hence, experimental
investigations into the rate and fitness effects of spontaneous mutations are central to the …

Mutation is the source of all heritable diversity, the essential material of evolution and
breeding. While mutation rates are often regarded as constant, variability in mutation rates …

Mutations are the ultimate source of all genetic variation. However, few direct estimates of
the contribution of mutation to molecular genetic variation are available. To address this …