Chronologically-aged skin displays multiple functional changes in both the dermis and the
epidermis. It appears that epidermal dysfunction, compromised permeability homeostasis …

Relentless, repetitive itching and scratching is a debilitating feature of many chronic
inflammatory skin disorders such as atopic dermatitis. While well known clinically, this itch …

Atopic dermatitis, also known as atopic eczema, is a chronic inflammatory skin disease
characterized by red pruritic skin lesions, xerosis, ichthyosis, and skin pain. Among the …

In dermatological research, 2, 4-dinitrochlorbenzene (DNCB)-induced atopic dermatitis (AD)
is a standard model as it displays many disease-associated characteristics of human AD …

The epidermis is a barrier that prevents water loss while kee** harmful substances from
penetrating the host. The impermeable cornified layer of the stratum corneum is maintained …

Atopic dermatitis (AD) is a chronic inflammatory skin disease presenting with recurrent
eczematous lesions and intense pruritus. It is common and affects both children and adults …

As the outermost layer of the skin, the epidermis is playing a major role in organism
homeostasis providing the first barrier against external aggressions. Although considered as …

Eosinophilic esophagitis (EoE) is a chronic, allergen-driven inflammatory disease of the
esophagus characterized predominantly by eosinophilic inflammation, leading to …

Identifying the function of kallikrein-related peptidases (KLKs) in the epidermis has elicited
great interest over recent decades. KLKs comprise 15 serine proteases, and their activities …

Skin appearance is essential for self‐esteem and quality of life; consequently, skin care
products represent a huge market. In particular, cosmeceuticals constitute a hybrid category …