Transfer RNA (tRNA) is an adapter molecule that links a specific codon in mRNA with its
corresponding amino acid during protein synthesis. tRNAs are enzymatically modified post …

Abstract tRNAs are key adaptor molecules that decipher the genetic code during translation
of mRNAs in protein synthesis. In contrast to the traditional view of tRNAs as ubiquitously …

Transfer RNAs (tRNAs) play a central role in protein translation. Studying them has been
difficult in part because a simple method to simultaneously quantify their abundance and …

Measurements of cellular tRNA abundance are hampered by pervasive blocks to cDNA
synthesis at modified nucleosides and the extensive similarity among tRNA genes. We …

The human genome encodes hundreds of transfer RNA (tRNA) genes but their individual
contribution to the tRNA pool is not fully understood. Deep sequencing of tRNA transcripts …

tRNAs are short noncoding RNAs required for protein translation. The human genome
includes more than 600 putative tRNA genes, many of which are considered redundant …

Small non-coding RNAs (sncRNAs) play critical roles in multiple regulatory processes,
including transcription, post-transcription, and translation. Emerging evidence reveals the …

Different tissues express genes with particular codon usage and anticodon tRNA
repertoires. However, the codon–anticodon co‐adaptation in humans is not completely …

The TRM10 family of methyltransferases is responsible for the N 1-methylation of purines at
position 9 of tRNAs in Archaea and Eukarya. The human genome encodes three TRM10 …

Prostate cancer is the most commonly diagnosed malignancy and the third leading cause of
cancer deaths. GWAS have identified variants associated with prostate cancer susceptibility; …