Short-chain fatty acids (SCFAs), the main metabolites produced by bacterial fermentation of
dietary fibre in the gastrointestinal tract, are speculated to have a key role in microbiota–gut …

The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

Impairment of the blood–brain barrier (BBB) integrity is implicated in the numerous
neurological disorders associated with neuroinflammation, neurodegeneration and aging. It …

Butyrate, a main product of gut microbial fermentation, has been recognized as an important
mediator of gut microbiota regulation in whole body energy homeostasis. However, the …

Background Chronic cerebral hypoperfusion (CCH) underlies secondary brain injury
following certain metabolic disorders and central nervous system (CNS) diseases …

The intestinal microbiota influence neurodevelopment, modulate behavior, and contribute to
neurological disorders. However, a functional link between gut bacteria and …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most
common cause for dementia. There are many hypotheses about AD, including abnormal …

Parkinson's disease (PD) patients display alterations in gut microbiota composition.
However, mechanism between gut microbial dysbiosis and pathogenesis of PD remains …

Animals share an intimate and life-long partnership with a myriad of resident microbial
species, collectively referred to as the microbiota. Symbiotic microbes have been shown to …

Gut microbial dysbiosis and alteration of microbial metabolites in Parkinson's disease (PD)
have been increasingly reported. Dysbiosis in the composition and abundance of gut …