Systemic lupus erythematosus: diagnosis and clinical management

A Fava, M Petri - Journal of autoimmunity, 2019 - Elsevier
Systemic lupus erythematosus (SLE) is a worldwide chronic autoimmune disease which
may affect every organ and tissue. Genetic predisposition, environmental triggers, and the …

[HTML][HTML] Immunological pathogenesis of inflammatory bowel disease

SH Lee, J eun Kwon, ML Cho - Intestinal research, 2018 - synapse.koreamed.org
Inflammatory bowel disease (IBD) is a chronic inflammatory state of the gastrointestinal tract
and can be classified into 2 main clinical phenomena: Crohn's disease (CD) and ulcerative …

Current and emerging therapeutic targets for IBD

MF Neurath - Nature Reviews Gastroenterology & Hepatology, 2017 - nature.com
Various therapeutic advances have led to a paradigm shift in the clinical management of
patients with IBD. The introduction of immunosuppressive (such as azathioprine) and …

Immunopathogenesis of IBD: current state of the art

HSP De Souza, C Fiocchi - Nature reviews Gastroenterology & …, 2016 - nature.com
IBD is a chronic inflammatory condition of the gastrointestinal tract encompassing two main
clinical entities: Crohn's disease and ulcerative colitis. Although Crohn's disease and …

Pharmacotherapy of generalized myasthenia gravis with special emphasis on newer biologicals

D Menon, V Bril - Drugs, 2022 - Springer
Myasthenia gravis (MG) is a chronic, fluctuating, antibody-mediated autoimmune disorder
directed against the post-synaptic neuromuscular junctions of skeletal muscles, resulting in …

RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer

A Jbara, KT Lin, C Stossel, Z Siegfried, H Shqerat… - Nature, 2023 - nature.com
Pancreatic ductal adenocarcinoma (PDA) is characterized by aggressive local invasion and
metastatic spread, leading to high lethality. Although driver gene mutations during PDA …

Mycophenolate mofetil, azathioprine and tacrolimus: mechanisms in rheumatology

JCA Broen, JM van Laar - Nature Reviews Rheumatology, 2020 - nature.com
The introduction of biologic DMARDs into rheumatology has resulted in a substantial
reduction of the burden of many rheumatic diseases. In the slipstream of the success …

Pathogenesis of inflammatory bowel disease and recent advances in biologic therapies

DH Kim, JH Cheon - Immune network, 2017 - synapse.koreamed.org
Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory disorder with an
unknown etiology. IBD is composed of two different disease entities: Crohn's disease (CD) …

American Gastroenterological Association Institute technical review on prevention and treatment of hepatitis B virus reactivation during immunosuppressive drug …

RP Perrillo, R Gish, YT Falck-Ytter - Gastroenterology, 2015 - gastrojournal.org
This article has an accompanying continuing medical education activity on page e16.
Learning Objective: Upon completion of the CME activity, successful learners will be able to …

The role of immune and inflammatory cells in idiopathic pulmonary fibrosis

O Desai, J Winkler, M Minasyan, EL Herzog - Frontiers in medicine, 2018 - frontiersin.org
The contribution of the immune system to idiopathic pulmonary fibrosis (IPF) remains poorly
understood. While most sources agree that IPF does not result from a primary …