[HTML][HTML] The role of adipose tissue mitochondria: regulation of mitochondrial function for the treatment of metabolic diseases
Mitochondria play a key role in maintaining energy homeostasis in metabolic tissues,
including adipose tissues. The two main types of adipose tissues are the white adipose …
including adipose tissues. The two main types of adipose tissues are the white adipose …
The role of leucine and its metabolites in protein and energy metabolism
Leucine (Leu) is a nutritionally essential branched-chain amino acid (BCAA) in animal
nutrition. It is usually one of the most abundant amino acids in high-quality protein foods …
nutrition. It is usually one of the most abundant amino acids in high-quality protein foods …
[HTML][HTML] Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes
Digested dietary fats are taken up by enterocytes where they are assembled into pre-
chylomicrons in the endoplasmic reticulum followed by transport to the Golgi for maturation …
chylomicrons in the endoplasmic reticulum followed by transport to the Golgi for maturation …
Mitochondrial dysfunction in obesity
JC Bournat, CW Brown - Current Opinion in Endocrinology …, 2010 - journals.lww.com
Mitochondria play central roles in ATP production, energy expenditure, and disposal of ROS.
Excessive energy substrates lead to mitochondrial dysfunction with consequential effects on …
Excessive energy substrates lead to mitochondrial dysfunction with consequential effects on …
Mitochondrial (dys) function in adipocyte (de) differentiation and systemic metabolic alterations
In mammals, adipose tissue, composed of BAT and WAT, collaborates in energy partitioning
and performs metabolic regulatory functions. It is the most flexible tissue in the body …
and performs metabolic regulatory functions. It is the most flexible tissue in the body …
Molecular mechanisms of alcoholic fatty liver
Alcoholic fatty liver is a potentially pathologic condition which can progress to
steatohepatitis, fibrosis, and cirrhosis if alcohol consumption is continued. Alcohol exposure …
steatohepatitis, fibrosis, and cirrhosis if alcohol consumption is continued. Alcohol exposure …
Shared pathways for neuroprogression and somatoprogression in neuropsychiatric disorders
Activated immune-inflammatory, oxidative and nitrosative stress (IO&NS) pathways and
consequent mitochondrial aberrations are involved in the pathophysiology of psychiatric …
consequent mitochondrial aberrations are involved in the pathophysiology of psychiatric …
[HTML][HTML] Protective role of mitochondrial uncoupling proteins against age-related oxidative stress in type 2 diabetes mellitus
The accumulation of oxidative damage to DNA and other biomolecules plays an important
role in the etiology of aging and age-related diseases such as type 2 diabetes mellitus …
role in the etiology of aging and age-related diseases such as type 2 diabetes mellitus …
[HTML][HTML] Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: a key to lean phenotype
We are facing a revival of the strategy to counteract obesity and associated metabolic
disorders by inducing thermogenesis mediated by mitochondrial uncoupling protein-1 …
disorders by inducing thermogenesis mediated by mitochondrial uncoupling protein-1 …
Fine particulate matter induces adipose tissue expansion and weight gain: Pathophysiology
L Della Guardia, L Wang - Obesity Reviews, 2023 - Wiley Online Library
Dysregulations in energy balance represent a major driver of obesity. Recent evidence
suggests that environmental factors also play a pivotal role in inducing weight gain. Chronic …
suggests that environmental factors also play a pivotal role in inducing weight gain. Chronic …