The transferability and clinical value of genetic risk scores (GRSs) across populations
remain limited due to an imbalance in genetic studies across ancestrally diverse …

Exploring the genetic loci underlying economic traits is foundational for innovation in
modern animal breeding technology. Genome‐wide association studies (GWAS) have been …

Disease variants identified by genome-wide association studies (GWAS) tend to overlap
with expression quantitative trait loci (eQTLs), but it remains unclear whether this overlap is …

Seed oil content (SOC) is a highly important and complex trait in oil crops. Here, we
decipher the genetic basis of natural variation in SOC of Brassica napus by genome-and …

Background Genome‐wide association studies (GWASs) have identified thousands of
genetic variants that are associated with many complex traits. However, their biological …

Metastatic castration-resistant prostate cancer is typically lethal, exhibiting intrinsic or
acquired resistance to second-generation androgen-targeting therapies and minimal …

Panicle architecture is a key determinant of rice grain yield and is mainly determined at the 1-
2 mm young panicle stage. Here, we investigated the transcriptome of the 1-2 mm young …

Abstract We introduce Proteome-Wide Association Study (PWAS), a new method for
detecting gene-phenotype associations mediated by protein function alterations. PWAS …

Genetic mechanisms of blood pressure (BP) regulation remain poorly defined. Using kidney-
specific epigenomic annotations and 3D genome information we generated and validated …

Our earlier work has shown that genomic risk for schizophrenia converges with early life
complications in affecting risk for the disorder and sex-biased neurodevelopmental …