Tumor development and metastasis are facilitated by the complex interactions between
cancer cells and their microenvironment, which comprises stromal cells and extracellular …

Background: Thanks to the rapid development of computer-based systems and deep-
learning-based algorithms, artificial intelligence (AI) has long been integrated into the …

The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

Metastasis, the spread of cancer from a primary site to distant organs, is an important
challenge in oncology. This Review explores the complexities of immune escape …

Tertiary lymphoid structures (TLS) are clusters of immune cells that resemble and function
similarly to secondary lymphoid organs (SLOs). While TLS is generally associated with an …

Neoantigens play a pivotal role in the field of tumour therapy, encompassing the stimulation
of anti-tumour immune response and the enhancement of tumour targeting capability …

Background Cancer is caused by a combination of genetic and epigenetic abnormalities.
Current cancer therapies are limited due to the complexity of their mechanism, underlining …

Artificial intelligence in health care has experienced remarkable innovation and progress in
the last decade. Significant advancements can be attributed to the utilization of artificial …

Immunotherapy offers the potential for durable clinical benefit but calls into question the
association between tumor size and outcome that currently forms the basis for imaging …

Simple Summary Despite recent advances in diagnosis and therapy, malignant melanoma
poses a significant problem both to clinicians and cancer researchers due to its resistance to …