The emerging roles of NGS in clinical oncology and personalized medicine
Next-generation sequencing (NGS) has been increasingly popular in genomics studies over
the last decade, as new sequencing technology has been created and improved. Recently …
the last decade, as new sequencing technology has been created and improved. Recently …
Characterizing genetic alterations related to radioiodine avidity in metastatic thyroid cancer
Z Mu, X Zhang, D Sun, Y Sun, C Shi… - The Journal of …, 2024 - academic.oup.com
Context Patients with differentiated thyroid cancer (DTC) with distant metastasis (DM) are
usually not recognized as radioactive iodine (RAI)-refractory DTC in a timely manner. The …
usually not recognized as radioactive iodine (RAI)-refractory DTC in a timely manner. The …
Fusion oncogenes in patients with locally advanced or distant metastatic differentiated thyroid cancer
G Ju, Y Sun, H Wang, X Zhang, Z Mu… - The Journal of …, 2024 - academic.oup.com
Context Fusion oncogenes are involved in the underlying pathology of advanced
differentiated thyroid cancer (DTC), and even the cause of radioactive iodine (RAI) …
differentiated thyroid cancer (DTC), and even the cause of radioactive iodine (RAI) …
Initial Experiences of selective RET inhibitor selpercatinib in adults with metastatic differentiated thyroid carcinoma and medullary thyroid carcinoma: real-World case …
Simple Summary Recently, selpercatinib, a highly selective inhibitor of RET receptor
tyrosine kinase, has been used for RET-altered thyroid cancer. However, real-world data of …
tyrosine kinase, has been used for RET-altered thyroid cancer. However, real-world data of …
[HTML][HTML] Distinctive role of DICER1 mutations in distant metastatic thyroid cancer
C Shi, Z Mu, W Guo, X Zhang, D Sun… - Chinese Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Objective This study investigated the clinical significance of DICER1 mutations in patients
with distant metastatic follicular cell-derived thyroid cancer (FDTC). Methods This study …
with distant metastatic follicular cell-derived thyroid cancer (FDTC). Methods This study …
[HTML][HTML] The value of NGS-based multi-gene testing for differentiation of benign from malignant and risk stratification of thyroid nodules
M Fei, D Ding, X Ouyang, W Shen, F Zhang… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Background Fine-needle aspiration (FNA) biopsy is typically used in conjunction with
cytopathologic evaluation to differentiate between benign and malignant thyroid nodules …
cytopathologic evaluation to differentiate between benign and malignant thyroid nodules …
Practice of Molecular Detection of Thyroid Fine-Needle Aspiration Specimen in China
Abstracts Thyroid tumors are common endocrine disorders, including benign, low risk, and
malignant tumors. Ultrasound-guided fine-needle aspiration (FNA) is widely applied as a …
malignant tumors. Ultrasound-guided fine-needle aspiration (FNA) is widely applied as a …
Next-Generation sequencing genomic landscape of Chinese thyroid tumors
XF Chen, PC Yu, WD Ye, PZ Han, YL Wang - 2023 - researchsquare.com
Objective: Clinical practice can benefit greatly from the use of next-generation sequencing to
identify gene alterations in thyroid cancer. Our study aimed to clarify the thyroid cancer's …
identify gene alterations in thyroid cancer. Our study aimed to clarify the thyroid cancer's …