Cancer is characterized by increased oxidative stress, an imbalance between reactive
oxygen species (ROS) and antioxidants. Enhanced ROS accumulation, as a result of …

Remarkable interest has risen in the idea that oxidative/nitrosative stress is mediated in the
etiology of numerous human diseases. Oxidative/Nitrosative stress is the result of an …

Transition metal ions are key elements of various biological processes ranging from oxygen
formation to hypoxia sensing, and therefore, their homeostasis is maintained within strict …

Oxidative/nitrosative stress, a pervasive condition of increased amounts of reactive
oxygen/nitrogen species, is now recognized to be a prominent feature of many acute and …

Background: Glutathione is a ubiquitous thiol-containing tripeptide, which plays a central
role in cell biology. It is implicated in the cellular defence against xenobiotics and naturally …

As we gain a better understanding of the factors affecting cancer etiology, we can design
improved treatment strategies. Over the past three to four decades, there have been …

The glutathione (GSH) content of cancer cells is particularly relevant in regulating mutagenic
mechanisms, DNA synthesis, growth, and multidrug and radiation resistance. In malignant …

After a brief discussion of lipid peroxidation mechanism and the action of antioxidants and
their potential to exhibit prooxidant effects, we give an overview on the clinical relevance of …

Glutamine is a multifaceted amino acid used for hepatic urea synthesis, renal
ammoniagenesis, gluconeogenesis in both liver and kidney, and as a major respiratory fuel …

This review provides a comprehensive overview of the functional roles of disulfide bonds
and their relevance to human disease. The critical roles of disulfide bonds in protein …