Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …

Cells have traditionally been viewed either as independently moving entities or as
somewhat static parts of tissues. However, it is now clear that in many cases, multiple cells …

Cell motion inside dense tissues governs many biological processes, including embryonic
development and cancer metastasis, and recent experiments suggest that these tissues …

From coffee beans flowing in a chute to cells remodelling in a living tissue, a wide variety of
close-packed collective systems—both inert and living—have the potential to jam. The …

The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each
comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …

Although collective cell motion plays an important role, for example during wound healing,
embryogenesis, or cancer progression, the fundamental rules governing this motion are still …

In active matter, particles typically experience mediated interactions, which are not
constrained by Newton's third law and are therefore generically non-reciprocal. Non …

Pressure is the mechanical force per unit area that a confined system exerts on its container.
In thermal equilibrium, it depends only on bulk properties—such as density and temperature …

In embryonic development or tumour evolution, cells often migrate collectively within
confining tracks defined by their microenvironment,. In some of these situations, the …

We introduce an Active Vertex Model (AVM) for cell-resolution studies of the mechanics of
confluent epithelial tissues consisting of tens of thousands of cells, with a level of detail …