Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Conquering the hypoxia limitation for photodynamic therapy
Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However …
Clinical development of metal complexes as photosensitizers for photodynamic therapy of cancer
J Karges - Angewandte chemie international edition, 2022 - Wiley Online Library
Cancer has emerged over the last decades as one of the deadliest diseases in the world.
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …
Cancer therapeutics based on diverse energy sources
Light-based phototherapy has been developed for cancer treatment owing to its non-
invasiveness and spatiotemporal control. Despite the unique merits of phototherapy, one …
invasiveness and spatiotemporal control. Despite the unique merits of phototherapy, one …
Innovative strategies for hypoxic‐tumor photodynamic therapy
Despite its clinical promise, photodynamic therapy (PDT) suffers from a key drawback
associated with its oxygen‐dependent nature, which limits its effective use against hypoxic …
associated with its oxygen‐dependent nature, which limits its effective use against hypoxic …
Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics
Brain cancer, especially the most common type of glioblastoma, is highly invasive and
known as one of the most devastating and deadly neoplasms. Despite surgical and medical …
known as one of the most devastating and deadly neoplasms. Despite surgical and medical …
Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …
Near-infrared light-initiated molecular superoxide radical generator: rejuvenating photodynamic therapy against hypoxic tumors
M Li, J **a, R Tian, J Wang, J Fan, J Du… - Journal of the …, 2018 - ACS Publications
Hypoxia, a quite universal feature in most solid tumors, has been considered as the
“Achilles' heel” of traditional photodynamic therapy (PDT) and substantially impairs the …
“Achilles' heel” of traditional photodynamic therapy (PDT) and substantially impairs the …
Nanozyme decorated metal–organic frameworks for enhanced photodynamic therapy
Metal–organic frameworks (MOFs) have been used for photodynamic therapy (PDT) of
cancers by integrating photosensitizers, which cause cytotoxic effects on cancer cells by …
cancers by integrating photosensitizers, which cause cytotoxic effects on cancer cells by …
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
The reactive oxygen species (ROS)-mediated mechanism is the major cause underlying the
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …
efficacy of photodynamic therapy (PDT). The PDT procedure is based on the cascade of …