Stabilizing and modulating color by copigmentation: Insights from theory and experiment

P Trouillas, JC Sancho-García, V De Freitas… - Chemical …, 2016 - ACS Publications
Natural anthocyanin pigments/dyes and phenolic copigments/co-dyes form noncovalent
complexes, which stabilize and modulate (in particular blue, violet, and red) colors in …

Experimental binding energies in supramolecular complexes

F Biedermann, HJ Schneider - Chemical reviews, 2016 - ACS Publications
On the basis of many literature measurements, a critical overview is given on essential
noncovalent interactions in synthetic supramolecular complexes, accompanied by analyses …

Glycomimetics versus multivalent glycoconjugates for the design of high affinity lectin ligands

S Cecioni, A Imberty, S Vidal - Chemical reviews, 2015 - ACS Publications
One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …

Stabilization and structure calculations for noncovalent interactions in extended molecular systems based on wave function and density functional theories

KE Riley, M Pitonák, P Jurecka, P Hobza - Chemical Reviews, 2010 - ACS Publications
More than 20 years ago, we published in Chemical ReViews a paper entitled
“Intermolecular Interactions between Medium-Sized Systems. Nonempirical and Empirical …

Entropy-enthalpy compensation: role and ramifications in biomolecular ligand recognition and design

JD Chodera, DL Mobley - Annual review of biophysics, 2013 - annualreviews.org
Recent calorimetric studies of interactions between small molecules and biomolecular
targets have generated renewed interest in the phenomenon of entropy-enthalpy …

Classification of current scoring functions

J Liu, R Wang - Journal of chemical information and modeling, 2015 - ACS Publications
Scoring functions are a class of computational methods widely applied in structure-based
drug design for evaluating protein–ligand interactions. Dozens of scoring functions have …

Designing the nanoparticle–biomolecule interface for “targeting and therapeutic delivery”

E Mahon, A Salvati, FB Bombelli, I Lynch… - Journal of Controlled …, 2012 - Elsevier
The endogenous transport mechanisms which occur in living organisms have evolved to
allow selective transport and processing operate on a scale of tens of nanometers. This …

Ligand-binding affinity estimates supported by quantum-mechanical methods

U Ryde, P Soderhjelm - Chemical Reviews, 2016 - ACS Publications
One of the largest challenges of computational chemistry is calculation of accurate free
energies for the binding of a small molecule to a biological macromolecule, which has …

Grid inhomogeneous solvation theory: hydration structure and thermodynamics of the miniature receptor cucurbit [7] uril

CN Nguyen, T Kurtzman Young… - The Journal of chemical …, 2012 - pubs.aip.org
The displacement of perturbed water upon binding is believed to play a critical role in the
thermodynamics of biomolecular recognition, but it is nontrivial to unambiguously define and …

An effective MM/GBSA protocol for absolute binding free energy calculations: A case study on SARS-CoV-2 spike protein and the human ACE2 receptor

N Forouzesh, N Mishra - Molecules, 2021 - mdpi.com
The binding free energy calculation of protein–ligand complexes is necessary for research
into virus–host interactions and the relevant applications in drug discovery. However, many …