In recent decades pharmaceutics and drug delivery have become increasingly critical in the
pharmaceutical industry due to longer time, higher cost, and less productivity of new …

Dendrimers are novel polymeric nanoarchitectures characterized by hyper-branched 3D-
structure having multiple functional groups on the surface that increases their functionality …

1. DENDRIMERS AND GENE DELIVERY Gene therapy represents a promising option for
the treatment of diseases such as inherited disorders, viral infections, and cancers. 1− 3 A …

Dendrimers are three-dimensional macromolecular structures originating from a central core
molecule and surrounded by successive addition of branching layers (generation). These …

Nowadays, gene delivery for therapeutic objects is considered one of the most promising
strategies to cure both the genetic and acquired diseases of human. The design of efficient …

Non-viral gene delivery vectors have lagged far behind viral ones in the current pipeline of
clinical trials of gene therapy nanomedicines. Even when non-viral nanovectors pose less …

Graphene oxide polyamidoamine (GO-PAMAM) was incorporated into polyamide network
via interfacial polymerization to prepare novel membranes. Several characterization …

Cancers are increasing in prevalence and many challenges remain for their treatment, such
as chemoresistance and toxicity. In this context, siRNA-based therapeutics have many …

Dendrimers are an excellent candidate that exhibits higher proficiency in biomedical
applications such as drug delivery, inhibition and/or targeting gene delivery. The use of …

In recent years innovative nanostructures are attracting increasing interest and, among
them, dendrimers have shown several fields of application. Dendrimers can be designed …