Although the biological functions of cell and tissue can be regulated by biochemical factors
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …

Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …

Over the last decade, numerous biopolymers have received more attention in medical
applications involving novel biomaterials because of their biocompatibility, biodegradability …

During recent decades vast and continuously increasing numbers of biomedical implants
have been introduced for continuous use in the human body. Since the early cemented hip …

This review reports the promising prospects of poly (lactic acid)(PLA) based nanostructured
materials considering two of their main potential uses, packaging and tissue engineering …

A key for long-term survival and function of biomaterials is that they do not elicit a detrimental
immune response. As biomaterials can have profound impacts on the host immune …

In biomaterials science, it is nowadays well accepted that improving the biointegration of
dental and orthopedic implants with surrounding tissues is a major goal. However, implant …

Topography, among other physical factors such as substrate stiffness and extracellular
forces, is known to have a great influence on cell behaviours. Optimization of topographical …

All cells exist within the context of a three-dimensional microenvironment in which they are
exposed to mechanical and physical cues. These cues can be disrupted through …

Recent progress in the design and application of artificial cellular microenvironments and
nanoenvironments has revealed the extraordinary ability of cells to adjust their cytoskeletal …