In much of the world antimicrobial drugs are sold without prescription or oversight by health-
care professionals. The scale and effect of this practice is unknown. We systematically …

This review looks at the critical role of vitamin D in improving barrier function, production of
antimicrobial peptides including cathelicidin and some defensins, and immune modulation …

Recent data for the global burden of disease reflect major demographic and lifestyle
changes, leading to a rise in non-communicable diseases. Most countries with high levels of …

Tuberculosis (TB) is a leading cause worldwide of human mortality attributable to a single
infectious agent. Recent studies targeting candidate genes and “case-control” association …

BACKGROUND: The possible effect of pulmonary tuberculosis (TB) on subsequent lung
cancer development has been suspected, but the evidence remains inconsistent. The …

Tuberculosis, a global threat to public health, is becoming untreatable due to widespread
drug resistance to frontline drugs such as the InhA‐inhibitor isoniazid. Historically, by …

Research on the infectious aspects of dental diseases has focused on the internal
development and the pathogenicity of dental biofilms, and comparably little attention has …

Whole-cell screening of Mycobacterium tuberculosis (Mtb) remains a mainstay of drug
discovery, but subsequent target elucidation often proves difficult. Conditional mutants that …

miR-21 has been shown to regulate multiple mRNAs and cause tumor progression and
metastasis. However, whether miR-21-mediated posttranscriptional regulation is involved in …

The development of improved vaccines against Mycobacterium tuberculosis has been
hindered by a limited understanding of the immune correlates of anti-tuberculosis protective …