Thioflavin T (ThT) has been widely used to investigate amyloid formation since 1989. While
concerns have recently been raised about its use as a probe specific for amyloid, ThT still …

Transthyretin (TTR) is a homotetrameric protein mainly synthesised by the liver and the
choroid plexus whose function is to carry the thyroid hormone thyroxine and the retinol …

The tetrameric thyroxine transport protein transthyretin (TTR) forms amyloid fibrils upon
dissociation and monomer unfolding. The aggregation of transthyretin has been reported as …

Assembly of rigid amyloid fibrils with their characteristic cross-β sheet structure is a
molecular signature of numerous neurodegenerative and non-neuropathic disorders …

Alzheimer's disease is associated with the deposition of the amyloid-β peptide (Aβ) into
extracellular senile plaques in the brain. In vitro and in vivo observations have indicated that …

Transthyretin (TTR) is a tetrameric protein transporting hormones in the plasma and brain,
which has many other activities that have not been fully acknowledged. TTR is a positive …

The progressive accumulation of transthyretin (TTR), a small protein that transports
thyroxine, in various organs and tissues is observed upon transthyretin amyloidosis, a …

Heart tissue can experience a progressive accumulation of transthyretin (TTR), a small four
subunit protein that transports holoretinol binding protein and thyroxine. This severe …

Tau abnormalities play a central role in several neurodegenerative diseases, collectively
known as tauopathies. In the present study, we examined whether mutant huntingtin (mHtt) …

Transthyretin (TTR) is a small tetrameric protein that aggregates, forming highly toxic
oligomers and fibrils. In the blood and cerebrospinal fluid, TTR can interact with various …