Our knowledge of the principles by which organ architecture develops through complex
collective cell behaviours is still limited. Recent work has shown that the shape of such …

Migration is a polarized cellular process that opposes a protrusive front edge to a retracting
trailing edge. From the front to the rear, actin-mediated forces sequentially promote cell …

The principle of self-assembly is believed to underlie the ability of cells to build amazingly
complex macromolecular structures such as the mitotic spindle. Most studies of self …

A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …

Microtubules are one of the three major cytoskeletal components in eukaryotic cells.
Heterodimers composed of GTP-bound α-and β-tubulin molecules polymerize to form …

Epithelia are exposed to multiple forms of stress. Keratin intermediate filaments are
abundant in epithelia and form cytoskeletal networks that contribute to cell type–specific …

Microtubules are highly dynamic structures whose regulation is crucial for cell division, cell
polarity, cell migration, or neuronal differentiation. Because they contribute to most cellular …

The basic features of the active filaments that use nucleotide hydrolysis to organise the
cytoplasm are remarkably similar in the majority of all cells and are either actin-like or tubulin …

Microtubules, the primary components of the chromosome segregation machinery, are
stabilized by longitudinal and lateral noncovalent bonds between the tubulin subunits …

Microtubules confined to the two-dimensional cortex of elongating plant cells must form a
parallel yet dispersed array transverse to the elongation axis for proper cell wall expansion …