Microbial consortia have been used in biotechnology processes, including fermentation,
waste treatment, and agriculture, for millennia. Today, synthetic biologists are increasingly …

Reconstructed microbial metabolic networks facilitate a mechanistic description of the
genotype–phenotype relationship through the deployment of constraint-based …

Microorganisms rarely live isolated in their natural environments but rather function in
consolidated and socializing communities. Despite the growing availability of high …

Much research has been invested into engineering microorganisms to perform desired
biotransformations; nonetheless, these efforts frequently fall short of expected results due to …

Interactions between microbial species are sometimes mediated by the exchange of small
molecules, secreted by one species and metabolized by another. Both one-way …

As the indispensable role of natural microbial communities in many aspects of life on Earth
is uncovered, the bottom-up engineering of synthetic microbial consortia with novel functions …

Trait-based approaches are an alternative to species-based approaches for functionally
linking individual organisms with community structure and dynamics. In the trait-based …

Polyhydroxyalkanoates (PHAs) are the biopolymer of choice if we look for a substitute of
petroleum-based non-biodegradable plastics. Microbial production of PHAs as carbon …

The use of microbial consortia for bioprocessing has been limited by our ability to reliably
control community composition and function simultaneously. Recent advances in synthetic …

Constraint-based modeling (CBM) has evolved as the core systems biology tool to map the
interrelations between genotype, phenotype, and external environment. The recent …