The morphological difference between glaucoma and other optic neuropathies

C Burgoyne - Journal of Neuro-ophthalmology, 2015 - journals.lww.com
The clinical phenomenon of cup** has 2 principal pathophysiologic components in all
optic neuropathies: prelaminar thinning and laminar deformation. We define prelaminar …

The connective tissue phenotype of glaucomatous cup** in the monkey eye-Clinical and research implications

H Yang, J Reynaud, H Lockwood, G Williams… - Progress in retinal and …, 2017 - Elsevier
In a series of previous publications we have proposed a framework for conceptualizing the
optic nerve head (ONH) as a biomechanical structure. That framework proposes important …

Influence of lamina cribrosa thickness and depth on the rate of progressive retinal nerve fiber layer thinning

EJ Lee, TW Kim, M Kim, H Kim - Ophthalmology, 2015 - Elsevier
Objective To determine whether lamina cribrosa (LC) depth (LCD) and LC thickness (LCT)
are associated with a faster rate of progressive retinal nerve fiber layer (RNFL) thinning in …

[HTML][HTML] Age-associated changes in the retinal nerve fiber layer and optic nerve head

NB Patel, M Lim, A Gajjar, KB Evans… - … & visual science, 2014 - jov.arvojournals.org
Purpose.: Optical coherence tomography (OCT) measures of the retinal nerve fiber layer
(RNFL) thickness and neuroretinal rim (NRR) parameters are often used as a surrogate for …

[HTML][HTML] Lamina cribrosa visibility using optical coherence tomography: comparison of devices and effects of image enhancement techniques

MJA Girard, TA Tun, R Husain… - … & visual science, 2015 - tvst.arvojournals.org
Purpose.: To compare the visibility of the lamina cribrosa (LC) in optic disc images acquired
from 60 glaucoma and 60 control subjects using three optical coherence tomography (OCT) …

The non-human primate experimental glaucoma model

CF Burgoyne - Experimental eye research, 2015 - Elsevier
The purpose of this report is to summarize the current strengths and weaknesses of the non-
human primate (NHP) experimental glaucoma (EG) model through sections devoted to its …

[HTML][HTML] Displacement of the lamina cribrosa in response to acute intraocular pressure elevation in normal individuals of African and European descent

MA Fazio, JK Johnstone, B Smith… - … & visual science, 2016 - tvst.arvojournals.org
Purpose: To assess if the in vivo mechanical displacement of the anterior laminar cribrosa
surface (ALCS) as a response of an acute elevation in intraocular pressure (IOP) differs in …

Serial changes in lamina cribrosa depth and neuroretinal parameters in glaucoma: impact of choroidal thickness

JR Vianna, VR Lanoe, J Quach, GP Sharpe… - Ophthalmology, 2017 - Elsevier
Purpose To determine whether:(1) change in lamina cribrosa depth occurs more frequently
than change in neuroretinal parameters in glaucoma, and (2) Bruch's membrane or anterior …

Biomechanical responses of lamina cribrosa to intraocular pressure change assessed by optical coherence tomography in glaucoma eyes

H Quigley, K Arora, S Idrees, F Solano… - … & visual science, 2017 - iovs.arvojournals.org
Purpose: The purpose of this study was to measure change in anterior lamina cribrosa depth
(ALD) globally and regionally in glaucoma eyes at different intraocular pressures (IOP) …

[HTML][HTML] Factors influencing central lamina cribrosa depth: a multicenter study

H Luo, H Yang, SK Gardiner, C Hardin… - … & visual science, 2018 - jov.arvojournals.org
Purpose: To quantify the influence of ocular and demographic factors on central laminar
depth (LD) in healthy participants. Methods: A total of 362 normal subjects underwent optical …