[HTML][HTML] Viral Components Trafficking with (in) Extracellular Vesicles

F Rey-Cadilhac, F Rachenne, D Missé, J Pompon - Viruses, 2023 - mdpi.com
The global public health burden exerted by viruses partially stems from viruses' ability to
subdue host cells into creating an environment that promotes their multiplication (ie, pro …

The GFAP proteoform puzzle: How to advance GFAP as a fluid biomarker in neurological diseases

D Gogishvili, MIJ Honey, IMW Verberk… - Journal of …, 2025 - Wiley Online Library
Glial fibrillary acidic protein (GFAP) is a well‐established biomarker of reactive astrogliosis
in the central nervous system because of its elevated levels following brain injury and …

Deciphering protein secretion from the brain to Cerebrospinal Fluid for Biomarker Discovery

K Waury, R de Wit, IMW Verberk… - Journal of Proteome …, 2023 - ACS Publications
Cerebrospinal fluid (CSF) is an essential matrix for the discovery of neurological disease
biomarkers. However, the high dynamic range of protein concentrations in CSF hinders the …

Distinct immunomodulation elicited by young versus aged extracellular vesicles in bone marrow-derived macrophages

D Livkisa, TL Lee, WT Yeh, MSV Jaimes, B Szomolay… - Immunity & …, 2024 - Springer
Background Previous research has indicated that extracellular vesicles (EVs) potentially
play significant roles in multiple ageing phenotypes. This study uses a factorial experimental …

PatchProt: hydrophobic patch prediction using protein foundation models

D Gogishvili, E Minois-Genin, J Van Eck… - Bioinformatics …, 2024 - academic.oup.com
Motivation Hydrophobic patches on protein surfaces play important functional roles in
protein–protein and protein-ligand interactions. Large hydrophobic surfaces are also …

Protein Disulfide Isomerase-Enriched Extracellular Vesicles from Bladder Cancer Cells Support Tumor Survival and Malignant Transformation in the Bladder

YF Lee, CH Wu, K Yuen, R Molony, C Silvers… - 2024 - researchsquare.com
Bladder cancer (BC) patients face high rates of disease recurrence, partially driven by the
cancer field effect. This effect is mediated in part by the release of pro-tumorigenic cargos in …