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A beginner's guide to eukaryotic genome annotation
M Yandell, D Ence - Nature Reviews Genetics, 2012 - nature.com
The falling cost of genome sequencing is having a marked impact on the research
community with respect to which genomes are sequenced and how and where they are …
community with respect to which genomes are sequenced and how and where they are …
Insect genomes: progress and challenges
In the wake of constant improvements in sequencing technologies, numerous insect
genomes have been sequenced. Currently, 1219 insect genome‐sequencing projects have …
genomes have been sequenced. Currently, 1219 insect genome‐sequencing projects have …
Genetics on the Fly: A Primer on the Drosophila Model System
KG Hales, CA Korey, AM Larracuente, DM Roberts - Genetics, 2015 - academic.oup.com
Fruit flies of the genus Drosophila have been an attractive and effective genetic model
organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them …
organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them …
The Release 6 reference sequence of the Drosophila melanogaster genome
RA Hoskins, JW Carlson, KH Wan, S Park… - Genome …, 2015 - genome.cshlp.org
Drosophila melanogaster plays an important role in molecular, genetic, and genomic studies
of heredity, development, metabolism, behavior, and human disease. The initial reference …
of heredity, development, metabolism, behavior, and human disease. The initial reference …
FlyBase: introduction of the Drosophila melanogaster Release 6 reference genome assembly and large-scale migration of genome annotations
G dos Santos, AJ Schroeder, JL Goodman… - Nucleic acids …, 2015 - academic.oup.com
Release 6, the latest reference genome assembly of the fruit fly Drosophila melanogaster,
was released by the Berkeley Drosophila Genome Project in 2014; it replaces their previous …
was released by the Berkeley Drosophila Genome Project in 2014; it replaces their previous …
Finishing the euchromatic sequence of the human genome
International Human Genome Sequencing Consortium - Nature, 2004 - nature.com
The sequence of the human genome encodes the genetic instructions for human
physiology, as well as rich information about human evolution. In 2001, the International …
physiology, as well as rich information about human evolution. In 2001, the International …
Hot-spot KIF5A mutations cause familial ALS
Heterozygous missense mutations in the N-terminal motor or coiled-coil domains of the
kinesin family member 5A (KIF5A) gene cause monogenic spastic paraplegia (HSP10) and …
kinesin family member 5A (KIF5A) gene cause monogenic spastic paraplegia (HSP10) and …
A whole-genome assembly of the domestic cow, Bos taurus
Background The genome of the domestic cow, Bos taurus, was sequenced using a mixture
of hierarchical and whole-genome shotgun sequencing methods. Results We have …
of hierarchical and whole-genome shotgun sequencing methods. Results We have …
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing
LR Susswein, ML Marshall, R Nusbaum… - Genetics in …, 2016 - nature.com
Purpose: Germ-line testing for panels of cancer genes using next-generation sequencing is
becoming more common in clinical care. We report our experience as a clinical laboratory …
becoming more common in clinical care. We report our experience as a clinical laboratory …
Finding the missing honey bee genes: lessons learned from a genome upgrade
Background The first generation of genome sequence assemblies and annotations have
had a significant impact upon our understanding of the biology of the sequenced species …
had a significant impact upon our understanding of the biology of the sequenced species …