Patients with isolated rapid-eye-movement sleep behaviour disorder (RBD) are commonly
regarded as being in the early stages of a progressive neurodegenerative disease involving …

Background Freezing of gait (FOG) is a common, disabling symptom of Parkinson's disease
(PD), but the mechanisms and treatments of FOG remain great challenges for clinicians and …

Parkinson's disease (PD) is the second most common neurodegenerative disease; gait
impairments are typical and are associated with increased fall risk and poor quality of life …

This review is part of the series on the clinical neurophysiology of movement disorders. It
focuses on Parkinson's disease and parkinsonism. The topics covered include the …

Cardinal motor symptoms in Parkinson's disease (PD) include bradykinesia, rest tremor
and/or rigidity. This symptomatology can additionally encompass abnormal gait, balance …

Background It is not clear how specific gait measures reflect disease severity across the
disease spectrum in Parkinson's disease (PD). Objective To identify the gait and mobility …

The aim of this meta-analysis is twofold:(a) to assess cognitive impairments in isolated rapid
eye movement (REM) sleep behavior disorder (iRBD) patients compared to healthy controls …

Study objectives Isolated rapid eye movement sleep behavior disorder (iRBD) is a
parasomnia characterized by dream enactment. It represents a prodromal state of α …

Neuroimaging studies in rapid eye movement sleep behavior disorder (RBD) can inform
fundamental questions about the pathogenesis of Parkinson's disease (PD). Across …

There is sufficient evidence that the pathological process that causes Parkinson's disease
begins years before the clinical diagnosis is made. Over the last 15 years, there has been …