Inflammation in diabetic retinopathy

J Tang, TS Kern - Progress in retinal and eye research, 2011 - Elsevier
Diabetes causes a number of metabolic and physiologic abnormalities in the retina, but
which of these abnormalities contribute to recognized features of diabetic retinopathy (DR) is …

Angiogenesis and inflammation crosstalk in diabetic retinopathy

M Capitão, R Soares - Journal of cellular biochemistry, 2016 - Wiley Online Library
Diabetic retinopathy (DR) is one of the most prevalent microvascular complications of
diabetes and one of the most frequent causes of blindness in active age. Etiopathogenesis …

Retinal oxygen: from animals to humans

RA Linsenmeier, HF Zhang - Progress in retinal and eye research, 2017 - Elsevier
This article discusses retinal oxygenation and retinal metabolism by focusing on
measurements made with two of the principal methods used to study O 2 in the retina …

The significance of vascular and neural apoptosis to the pathology of diabetic retinopathy

AJ Barber, TW Gardner… - … ophthalmology & visual …, 2011 - iovs.arvojournals.org
The most striking features of diabetic retinopathy are the vascular abnormalities that are
apparent by fundus examination. There is also strong evidence that diabetes causes …

[HTML][HTML] Kidney and eye diseases: common risk factors, etiological mechanisms, and pathways

CW Wong, TY Wong, CY Cheng, C Sabanayagam - Kidney international, 2014 - Elsevier
Chronic kidney disease is an emerging health problem worldwide. The eye shares striking
structural, developmental, and genetic pathways with the kidney, suggesting that kidney …

Diabetic retinopathy: targeting vasoregression

HP Hammes, Y Feng, F Pfister, M Brownlee - Diabetes, 2011 - pmc.ncbi.nlm.nih.gov
Most diabetes researchers and clinicians are aware of the major advances made in
understanding the pathobiology of proliferative diabetic retinopathy. However mechanisms …

Contribution of microglia‐mediated neuroinflammation to retinal degenerative diseases

MH Madeira, R Boia, PF Santos… - Mediators of …, 2015 - Wiley Online Library
Retinal degenerative diseases are major causes of vision loss and blindness worldwide and
are characterized by chronic and progressive neuronal loss. One common feature of retinal …

[HTML][HTML] Role of oxidative stress, inflammation, hypoxia and angiogenesis in the development of diabetic retinopathy

AS Al-Kharashi - Saudi journal of ophthalmology, 2018 - Elsevier
Diabetic retinopathy (DR) is a retinal disease which is one of the most severe complications
occuring due to diabetes mellitus and is a major cause of blindness. Patients who have …

[HTML][HTML] Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy

R Fernandes, SD Viana, S Nunes, F Reis - Biochimica Et Biophysica Acta …, 2019 - Elsevier
The increased prevalence of type 2 diabetes mellitus (T2DM) and life expectancy of diabetic
patients fosters the worldwide prevalence of retinopathy and nephropathy, two major …

Dysregulated CD200-CD200R signaling in early diabetes modulates microglia-mediated retinopathy

CW Pfeifer, JT Walsh, A Santeford, JB Lin… - Proceedings of the …, 2023 - pnas.org
Diabetic retinopathy (DR) is a neurovascular complication of diabetes. Recent investigations
have suggested that early degeneration of the neuroretina may occur prior to the …