Surgery and stress promote cancer metastasis: new outlooks on perioperative mediating mechanisms and immune involvement
E Neeman, S Ben-Eliyahu - Brain, behavior, and immunity, 2013 - Elsevier
Surgery for the removal of a primary tumor presents an opportunity to eradicate cancer or
arrest its progression, but is also believed to promote the outbreak of pre-existing …
arrest its progression, but is also believed to promote the outbreak of pre-existing …
Surgery as a risk factor for breast cancer recurrence and metastasis: mediating mechanisms and clinical prophylactic approaches
Y Goldfarb, S Ben-Eliyahu - Breast disease, 2007 - content.iospress.com
Surgical resection of the primary tumor is a necessary and effective treatment for breast
cancer patients. For various reasons discussed, we believe that the short postoperative …
cancer patients. For various reasons discussed, we believe that the short postoperative …
Perioperative use of β-blockers and COX-2 inhibitors may improve immune competence and reduce the risk of tumor metastasis
M Benish, I Bartal, Y Goldfarb, B Levi… - Annals of surgical …, 2008 - Springer
Background COX inhibitors and β-blockers were recently suggested to reduce cancer
progression through inhibition of tumor proliferation and growth factor secretion, induction of …
progression through inhibition of tumor proliferation and growth factor secretion, induction of …
Do Stress Responses Promote Leukemia Progression? An Animal Study Suggesting a Role for Epinephrine and Prostaglandin-E2 through Reduced NK Activity
S Inbar, E Neeman, R Avraham, M Benish, E Rosenne… - PloS one, 2011 - journals.plos.org
In leukemia patients, stress and anxiety were suggested to predict poorer prognosis.
Oncological patients experience ample physiological and psychological stress, potentially …
Oncological patients experience ample physiological and psychological stress, potentially …
Impact of brief exercise on peripheral blood NK cell gene and microRNA expression in young adults
S Radom-Aizik, F Zaldivar… - Journal of applied …, 2013 - journals.physiology.org
Natural killers (NK) cells are unique innate immune cells that increase up to fivefold in the
circulating blood with brief exercise and are known to play a key role in first-response …
circulating blood with brief exercise and are known to play a key role in first-response …
Does analgesia and condition influence immunity after surgery? Effects of fentanyl, ketamine and clonidine on natural killer activity at different ages
P Forget, V Collet, P Lavand'homme… - European Journal of …, 2010 - journals.lww.com
Materials and methods Rats undergoing laparotomy under sevoflurane anaesthesia were
assigned to receive saline, fentanyl (40 μg kg− 1), clonidine (10 μg kg− 1) or ketamine (10 …
assigned to receive saline, fentanyl (40 μg kg− 1), clonidine (10 μg kg− 1) or ketamine (10 …
In vivo suppression of NK cell cytotoxicity by stress and surgery: glucocorticoids have a minor role compared to catecholamines and prostaglandins
E Rosenne, L Sorski, L Shaashua, E Neeman… - Brain, behavior, and …, 2014 - Elsevier
Most in vitro and ex-vivo studies indicate a profound suppression of NK cell cytotoxicity
(NKCC) by glucocorticoids; while catecholamines and prostaglandins were reported both to …
(NKCC) by glucocorticoids; while catecholamines and prostaglandins were reported both to …
The influence of myeloid‐derived suppressor cells on angiogenesis and tumor growth after cancer surgery
J Wang, X Su, L Yang, F Qiao, Y Fang… - … journal of cancer, 2016 - Wiley Online Library
While myeloid‐derived suppressor cells (MDSCs) have been reported to participate in the
promotion of angiogenesis and tumor growth, little is known about their presence and …
promotion of angiogenesis and tumor growth, little is known about their presence and …
Single dose of dexamethasone is not associated with postoperative recurrence and mortality in breast cancer patients: a propensity-matched cohort study
MH Kim, DW Kim, S Park, JH Kim, KY Lee, J Hwang… - BMC cancer, 2019 - Springer
Background Dexamethasone is widely used in cancer patients despite the concern that
perioperative glucocorticoids may potentially cause immunosuppression. However, studies …
perioperative glucocorticoids may potentially cause immunosuppression. However, studies …
Autologous serum collected 1 h post-exercise enhances natural killer cell cytotoxicity
Natural Killer cells are cytotoxic lymphocytes that recognize and eliminate tumor cells.
Exercise enhances NK cell cytotoxic activity (NKCA), yet the underlying mechanisms are not …
Exercise enhances NK cell cytotoxic activity (NKCA), yet the underlying mechanisms are not …