Quantum chemistry calculations for metabolomics: Focus review

RM Borges, SM Colby, S Das, AS Edison… - Chemical …, 2021 - ACS Publications
A primary goal of metabolomics studies is to fully characterize the small-molecule
composition of complex biological and environmental samples. However, despite advances …

A map of mass spectrometry-based in silico fragmentation prediction and compound identification in metabolomics

CA Krettler, GG Thallinger - Briefings in Bioinformatics, 2021 - academic.oup.com
Metabolomics, the comprehensive study of the metabolome, and lipidomics—the large-scale
study of pathways and networks of cellular lipids—are major driving forces in enabling …

From QCEIMS to QCxMS: A tool to routinely calculate CID mass spectra using molecular dynamics

J Koopman, S Grimme - Journal of the American Society for Mass …, 2021 - ACS Publications
Mass spectrometry (MS) is a powerful tool in chemical research and substance identification.
For the computational modeling of electron ionization MS, we have developed the quantum …

A comprehensive database for DNA adductomics

G La Barbera, KD Nommesen, C Cuparencu… - Frontiers in …, 2022 - frontiersin.org
The exposure of human DNA to genotoxic compounds induces the formation of covalent
DNA adducts, which may contribute to the initiation of carcinogenesis. Liquid …

Computational risk assessment framework for the hazard analysis of bisphenols and quinone metabolites

S Pandit, P Singh, R Parthasarathi - Journal of Hazardous Materials, 2022 - Elsevier
Bisphenol A (BPA) is a widely used chemical in plastics but its proven harmful effects has
led to the replacement and production of its analogs that might also induce hazard as well …

Stochastic dynamic quantitative and 3D structural matrix assisted laser desorption/ionization mass spectrometric analyses of mixture of nucleosides

B Ivanova, M Spiteller - Journal of Molecular Structure, 2022 - Elsevier
The paper tackles issue of solid-state 3D structural analysis by means of matrix assisted
laser desorption/ionization mass spectrometry with a view of our innovative stochastic …

Determination of kinetic properties in unimolecular dissociation of complex systems from graph theory based analysis of an ensemble of reactive trajectories

AF Perez-Mellor, R Spezia - The Journal of Chemical Physics, 2021 - pubs.aip.org
In this paper, we report how graph theory can be used to analyze an ensemble of
independent molecular trajectories, which can react during the simulation time-length, and …

In Silico Tandem Mass Spectrometer: an Analytical and Fundamental Tool

A Carrà, R Spezia - Chemistry‐Methods, 2021 - Wiley Online Library
In this article, we summarize some aspects of the recently developed computational
approach to model and predict collision induced dissociation mass spectra. In particular, we …

Unlocking The Mysteries of DNA Adducts with Artificial Intelligence

S Arora, S Satija, A Mittal, S Solanki… - …, 2024 - Wiley Online Library
Cellular genome is considered a dynamic blueprint of a cell since it encodes genetic
information that gets temporally altered due to various endogenous and exogenous insults …

Computation of Mass Spectra Using Quantum Chemical Methods

JG Koopman - 2022 - bonndoc.ulb.uni-bonn.de
Mass spectrometry (MS) is widely used for the structural elucidation of compounds in a vast
variety of scientific research. Unfortunately, many methods that aim to predict mass spectra …