Fluorinated carbohydrates as chemical probes for molecular recognition studies. Current status and perspectives
This review provides an extensive summary of the effects of carbohydrate fluorination with
regard to changes in physical, chemical and biological properties with respect to regular …
regard to changes in physical, chemical and biological properties with respect to regular …
Pathogenesis of ocular toxoplasmosis
JR Smith, LM Ashander, SL Arruda, CA Cordeiro… - Progress in Retinal and …, 2021 - Elsevier
Ocular toxoplasmosis is a retinitis–almost always accompanied by vitritis and choroiditis–
caused by intraocular infection with Toxoplasma gondii. Depending on retinal location, this …
caused by intraocular infection with Toxoplasma gondii. Depending on retinal location, this …
[HTML][HTML] 'Click chemistry'synthesis of a library of 1, 2, 3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface …
Trypanosoma cruzi trans-sialidase (TcTS) plays a key role in the recognition and invasion of
host cells and in enabling the parasite to escape the human immune response. To explore …
host cells and in enabling the parasite to escape the human immune response. To explore …
Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase from Mycobacterium tuberculosis Using Substrate and Tetrafluorinated Substrate Analogues
KE Van Straaten, JRA Kuttiyatveetil… - Journal of the …, 2015 - ACS Publications
UDP-Galactopyranose mutase (UGM) is a flavin-containing enzyme that catalyzes the
reversible conversion of UDP-galactopyranose (UDP-Gal p) to UDP-galactofuranose (UDP …
reversible conversion of UDP-galactopyranose (UDP-Gal p) to UDP-galactofuranose (UDP …
Identification and Characterization of Eimeria tenella Microneme Protein (EtMIC8)
N Zhao, S Ming, L Sun, B Wang, H Li… - Microbiology …, 2021 - Am Soc Microbiol
ABSTRACT Microneme proteins (MICs) of Eimeria tenella play key roles in motility,
migration, attachment, and invasion processes. More than 20 apicomplexan parasite's MICs …
migration, attachment, and invasion processes. More than 20 apicomplexan parasite's MICs …
Lectin structures: classification based on the 3-D structures
Recent progress in structural biology has elucidated the three-dimensional structures and
carbohydrate-binding mechanisms of most lectin families. Lectins are classified into 48 …
carbohydrate-binding mechanisms of most lectin families. Lectins are classified into 48 …
Members of a novel protein family containing microneme adhesive repeat domains act as sialic acid-binding lectins during host cell invasion by apicomplexan …
Numerous intracellular pathogens exploit cell surface glycoconjugates for host cell
recognition and entry. Unlike bacteria and viruses, Toxoplasma gondii and other parasites of …
recognition and entry. Unlike bacteria and viruses, Toxoplasma gondii and other parasites of …
Neoglycolipid-based oligosaccharide microarray system: preparation of NGLs and their noncovalent immobilization on nitrocellulose-coated glass slides for …
Carbohydrate microarrays, since their advent in 2002, are revolutionizing studies of the
molecular basis of protein–carbohydrate interactions both in endogenous recognition …
molecular basis of protein–carbohydrate interactions both in endogenous recognition …
Vaccination with recombinant microneme proteins confers protection against experimental toxoplasmosis in mice
Toxoplasmosis, a zoonotic disease caused by Toxoplasma gondii, is an important public
health problem and veterinary concern. Although there is no vaccine for human …
health problem and veterinary concern. Although there is no vaccine for human …
Engineering and characterization of a novel Self Assembling Protein for Toxoplasma peptide vaccine in HLA-A*11:01, HLA-A*02:01 and HLA-B*07:02 transgenic …
K El Bissati, Y Zhou, SM Paulillo, SK Raman… - Scientific Reports, 2020 - nature.com
Fighting smart diseases requires smart vaccines. Novel ways to present protective
immunogenic peptide epitopes to human immune systems are needed. Herein, we focus on …
immunogenic peptide epitopes to human immune systems are needed. Herein, we focus on …