The gut microbiota regulates levels of serotonin (5-hydroxytryptamine (5-HT)) in the
intestinal epithelium and lumen,,,–. However, whether 5-HT plays a functional role in …

Organic cation transporters (OCT) 1, 2 and 3 and novel organic cation transporters (OCTN) 1
and 2 of the solute carrier 22 (SLC22) family are involved in the cellular transport of …

Active transport of neurotransmitters into synaptic vesicles is required for their subsequent
exocytotic release. In the monoamine system, this process is carried out by the vesicular …

Concurrent cocaine and alcohol use is among the most frequent drug combination, and
among the most dangerous in terms of deleterious outcomes. Cocaine increases …

The concentrative power of the transporters for dopamine (DAT), norepinephrine (NET), and
serotonin (SERT) is thought to be fueled by the transmembrane Na+ gradient, but it is …

Vesicular monoamine transporter 2 (VMAT2) is an essential component of the
monoaminergic neurotransmission system in the brain as it transports monoamine …

The ability of prokaryotic microbes to produce and respond to neurochemicals that are more
often associated with eukaryotic systems is increasingly recognized through the concept of …

The mouse hippocampal neuronal cell line HT22 is frequently used as an in vitro model to
investigate the role of hippocampal cholinergic neurons in cognitive functions. HT22 cells …

The serotonin transporter (SERT) readily takes up serotonin (5-HT), thereby regulating the
availability of 5-HT within the intestine. In the absence of SERT, 5-HT remains in the …

Albizia julibrissin Durazz is one of the most common herbs used for depression and anxiety
treatment, but its mechanism of action as an antidepressant or anxiolytic drug have not been …