Introduction Cardiovascular (CV) disorders are steadily increasing, making them the world's
most prevalent health issue. New research highlights the importance of insulin-like growth …

Accumulating evidence has indicated that insulin-like growth factor-1 (IGF-1) plays a specific
role in the intricate cascade of events of cardiovascular function, in addition to its well …

Objectives. The aim of our study was to analyse, in a wide group of essential hypertensive
patients without diabetes mellitus, the influence of metabolic syndrome (MS)(defined …

Atherosclerotic cardiovascular disease (CVD) is a major health problem in the United States
and around the world. Evidence accumulated over decades convincingly demonstrates that …

Background—It is unclear whether insulin and insulin-like growth factor-1 (IGF-1) are
independent determinants of left ventricular (LV) mass in essential hypertension. Methods …

It is widely accepted that there are two principal forms of cell death; namely, necrosis and
apoptosis. According to the classical view, necrosis is the major mechanism of …

Background In the general population, low IGF1 has been associated with higher
prevalence of cardiovascular disease and mortality. Objective To investigate the …

Objective—The metabolic and genetic correlates of circulating insulin-like growth factor-1
(IGF-1) and its main circulating carrier, IGF-1-binding-protein-3 (IGFBP-3), are unclear …

Conflicting evidence exists on the relationship between blood pressure (BP) and insulin-like
growth factor-1 (IGF-1). We reviewed available articles and pooled extrapolated regression …

This year, 2022, marks the 100th anniversary of the isolation of human insulin and its
administration to patients suffering from diabetes mellitus (DM). Insulin exerts many effects …