Curing cancer through precision medicine is the paramount aim of the new wave of
molecular and genomic therapies. Currently, whether patients with non-reproductive …

We now know that cancer is many different diseases, with great variation even within a
single histological subtype. With the current emphasis on develo** personalized …

Abstract Treatment with therapy targeting BRAF and MEK (BRAF/MEK) has revolutionized
care in melanoma and other cancers; however, therapeutic resistance is common and …

Background Identification of variable epidermal growth factor receptor (EGFR) gene
mutations in non-small cell lung cancer (NSCLC) is important for the selection of appropriate …

Lung cancer (LC), the leading cause of cancer-related deaths worldwide, is a complex and
highly heterogeneous disease. Additional to its biological complexity, LC patients are often …

In stark contrast to a few decades ago when lung cancer was predominantly a disease of
men who smoke, incidence rates of lung cancer in women are now comparable to or higher …

The global burden of cancer is growing and a wide disparity in the incidence, malignancy
and mortality of different types of cancer between each sex has been demonstrated. The sex …

Lung cancer is the leading cause of cancer death for women in multiple countries including
the United States. Women are exposed to unique risk factors that remain largely …

Sex differences in susceptibility, severity, and progression are prevalent for various diseases
in multiple organ systems. This phenomenon is particularly apparent in respiratory diseases …

Accumulating evidence suggested that both gut microbiome and sex play a critical role in
the efficacy of immune checkpoint blockade therapy. Considering the reciprocal relationship …