Due to their involvement in numerous biochemical pathways, neuropeptides have been the
focus of many recent research studies. Unfortunately, classic analytical methods, such as …

Neuropeptides are short peptides in the range of 3–40 residues that are secreted for cell-cell
communication in neuroendocrine systems. In the nervous system, neuropeptides comprise …

During the winter, hibernating mammals undergo extreme changes in physiology, which
allow them to survive several months without access to food. These animals enter a state of …

Blood-brain barrier (BBB) dysfunction is associated with an accumulation of neurotoxic
molecules and increased infiltration of peripheral cells within the brain parenchyma …

Glycopeptides in peptide or digested protein samples pose a number of analytical and
bioinformatics challenges beyond those posed by unmodified peptides or peptides with …

Quantitative mass spectrometry has been widely used to evaluate the concentrations of
molecules within a variety of biological matrices. Typically, such quantitative mass …

Cell–cell signaling peptides (eg, peptide hormones, neuropeptides) are among the largest
class of cellular transmitters and regulate a variety of physiological processes. To identify …

Protein database search engines are an integral component of mass spectrometry-based
peptidomic analyses. Given the unique computational challenges of peptidomics, many …

Certain probiotics have beneficial effects on the function of the central nervous system
through modulation of the gut-brain axis. Here, we describe a dynamic landscape of the …

Neuropeptides (NPs), a unique class of neuronal signaling molecules, participate in a
variety of physiological processes and diseases. Quantitative measurements of NPs provide …