Due to their involvement in numerous biochemical pathways, neuropeptides have been the
focus of many recent research studies. Unfortunately, classic analytical methods, such as …

Neuropeptides are short peptides in the range of 3–40 residues that are secreted for cell-cell
communication in neuroendocrine systems. In the nervous system, neuropeptides comprise …

Glycopeptides in peptide or digested protein samples pose a number of analytical and
bioinformatics challenges beyond those posed by unmodified peptides or peptides with …

Blood-brain barrier (BBB) dysfunction is associated with an accumulation of neurotoxic
molecules and increased infiltration of peripheral cells within the brain parenchyma …

Neuropeptides represent a unique class of signaling molecules that have garnered much
attention but require special consideration when identifications are gleaned from mass …

During the winter, hibernating mammals undergo extreme changes in physiology, which
allow them to survive several months without access to food. These animals enter a state of …

Protein database search engines are an integral component of mass spectrometry-based
peptidomic analyses. Given the unique computational challenges of peptidomics, many …

Certain probiotics have beneficial effects on the function of the central nervous system
through modulation of the gut-brain axis. Here, we describe a dynamic landscape of the …

Cell–cell signaling peptides (eg, peptide hormones, neuropeptides) are among the largest
class of cellular transmitters and regulate a variety of physiological processes. To identify …

The American lobster, Homarus americanus, is not only of considerable economic
importance but has also emerged as a premier model organism in neuroscience research …