Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of
enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are …

Introduction In recent years, it has been described that the dysbiosis of the intestinal
microbiota plays a transcendental role in several pathologies. In this sense, the importance …

Many studies have reported abnormal gut microbiota in individuals with Autism Spectrum
Disorders (ASD), suggesting a link between gut microbiome and autism-like behaviors …

Background Autism spectrum disorders (ASD) are complex neurobiological disorders that
impair social interactions and communication and lead to restricted, repetitive, and …

Evidence supporting that gut problems are linked to ASD symptoms has been accumulating
both in humans and animal models of ASD. Gut microbes and their metabolites may be …

To date, no medication is proven to be effective in treating core symptoms of autism
spectrum disorder (ASD). Psychotropic medications are widely used to target emotional and …

Autism spectrum disorder is a diagnosis that includes significant social communication
deficits/delays along with restricted patterns of interests and behaviors. The prevalence of …

This study involved a randomized, controlled, single-blind 12-month treatment study of a
comprehensive nutritional and dietary intervention. Participants were 67 children and adults …

The role of glutathione in autism spectrum disorder (ASD) is emerging as a major topic, due
to its role in the maintenance of the intracellular redox balance. Several studies have …

Several lines of evidence implicate mitochondria in the pathophysiology of autism spectrum
disorder (ASD). In this review, we outline some of the evidence supporting this notion, as …