Brain–heart interaction after acute ischemic stroke

D Battaglini, C Robba, A Lopes da Silva… - Critical care, 2020 - Springer
Early detection of cardiovascular dysfunctions directly caused by acute ischemic stroke (AIS)
has become paramount. Researchers now generally agree on the existence of a …

Creation and application of virtual patient cohorts of heart models

SA Niederer, Y Aboelkassem… - … of the Royal …, 2020 - royalsocietypublishing.org
Patient-specific cardiac models are now being used to guide therapies. The increased use
of patient-specific cardiac simulations in clinical care will give rise to the development of …

[HTML][HTML] An electromechanics-driven fluid dynamics model for the simulation of the whole human heart

A Zingaro, M Bucelli, R Piersanti, F Regazzoni… - Journal of …, 2024 - Elsevier
We introduce a multiphysics and geometric multiscale computational model, suitable to
describe the hemodynamics of the whole human heart, driven by a four-chamber …

Demonstration of patient-specific simulations to assess left atrial appendage thrombogenesis risk

M García-Villalba, L Rossini, A Gonzalo… - Frontiers in …, 2021 - frontiersin.org
Atrial fibrillation (AF) alters left atrial (LA) hemodynamics, which can lead to thrombosis in
the left atrial appendage (LAA), systemic embolism and stroke. A personalized risk …

Polygonal surface processing and mesh generation tools for the numerical simulation of the cardiac function

M Fedele, A Quarteroni - International Journal for Numerical …, 2021 - Wiley Online Library
In order to simulate the cardiac function for a patient‐specific geometry, the generation of the
computational mesh is crucially important. In practice, the input is typically a set of …

Left atrial appendage closure for stroke prevention in atrial fibrillation: current status and perspectives

U Landmesser, C Skurk, A Tzikas, V Falk… - European heart …, 2024 - academic.oup.com
Atrial fibrillation (AF) is associated with an increased risk of stroke and systemic embolism,
and the left atrial appendage (LAA) has been identified as a principal source of …

A geometric multiscale model for the numerical simulation of blood flow in the human left heart

A Zingaro, I Fumagalli, L Dede, M Fedele… - arxiv preprint arxiv …, 2021 - arxiv.org
We present a new computational model for the numerical simulation of blood flow in the
human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian …

Hemodynamics of the heart's left atrium based on a variational multiscale-LES numerical method

A Zingaro, F Menghini, A Quarteroni - European Journal of Mechanics-B …, 2021 - Elsevier
In this paper, we investigate the haemodynamics of a left atrium (LA) by proposing a
computational model suitable to provide physically meaningful fluid dynamics indications …

[HTML][HTML] A bi-atrial statistical shape model for large-scale in silico studies of human atria: model development and application to ECG simulations

C Nagel, S Schuler, O Dössel, A Loewe - Medical Image Analysis, 2021 - Elsevier
Large-scale electrophysiological simulations to obtain electrocardiograms (ECG) carry the
potential to produce extensive datasets for training of machine learning classifiers to, eg …

[HTML][HTML] A comprehensive comparison of various patient-specific CFD models of the left atrium for atrial fibrillation patients

J Dueñas-Pamplona, JG García… - Computers in Biology …, 2021 - Elsevier
Background Recently, advances in medical imaging, segmentation techniques, and high-
performance computing have supported the use of patient-specific computational fluid …