Organotypic models of patient-specific tumours are revolutionizing our understanding of
cancer heterogeneity and its implications for personalized medicine. These advancements …

Cell migration is essential for physiological processes as diverse as development, immune
defence and wound healing. It is also a hallmark of cancer malignancy. Thousands of …

Chemical reactions tend to be conceptualized in terms of individual molecules transforming
into products, but are usually observed in experiments that probe the average behaviour of …

Pancreatic ductal adenocarcinoma (PDAC) is characterized by its fibrotic and stiff
extracellular matrix. However, how the altered cell/extracellular-matrix signalling contributes …

How the shape of embryos and organs emerges during development is a fundamental
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …