Understanding HDL metabolism and biology through in vivo tracer kinetics

AB Andraski, FM Sacks, M Aikawa… - … , and Vascular Biology, 2024 - Am Heart Assoc
HDL (high-density lipoprotein), owing to its high protein content and small size, is the
densest circulating lipoprotein. In contrast to lipid-laden VLDL (very-low-density lipoprotein) …

Reduced apolipoprotein M and adverse outcomes across the spectrum of human heart failure

JA Chirinos, L Zhao, Y Jia, C Frej, L Adamo, D Mann… - Circulation, 2020 - Am Heart Assoc
Background: Apo (apolipoprotein) M mediates the physical interaction between high-density
lipoprotein (HDL) particles and sphingosine-1-phosphate (S1P). Apo M exerts anti …

Apolipoprotein M/sphingosine-1-phosphate: novel effects on lipids, inflammation and kidney biology

LS Bisgaard, C Christoffersen - Current opinion in lipidology, 2019 - journals.lww.com
Apolipoprotein M/sphingosine-1-phosphate: novel effects on l... : Current Opinion in
Lipidology Apolipoprotein M/sphingosine-1-phosphate: novel effects on lipids, inflammation …

VLDL (very-low-density lipoprotein)-Apo E (apolipoprotein E) may influence Lp (a)(lipoprotein [a]) synthesis or assembly

M Croyal, V Blanchard, K Ouguerram… - … and Vascular Biology, 2020 - Am Heart Assoc
Objective: To clarify the association between PCSK9 (proprotein convertase subtilisin/kexin
type 9) and Lp (a)(lipoprotein [a]), we studied Lp (a) kinetics in patients with loss-of-function …

[HTML][HTML] Apolipoprotein M: a novel adipokine decreasing with obesity and upregulated by calorie restriction

V Sramkova, S Berend, M Siklova… - The American journal of …, 2019 - Elsevier
Background The adipose tissue (AT) is a secretory organ producing a wide variety of factors
that participate in the genesis of metabolic disorders linked to excess fat mass. Weight loss …

A high-throughput mass spectrometry-based assay for large-scale profiling of circulating human apolipoproteins [S]

V Blanchard, D Garçon, C Jaunet, K Chemello… - Journal of Lipid …, 2020 - ASBMB
Apolipoproteins govern lipoprotein metabolism and are promising biomarkers of metabolic
and cardiovascular diseases. Unlike immunoassays, MS enables the quantification and …

The adipocyte apolipoprotein M is negatively associated with inflammation

L Frances, M Croyal, S Pittet, LDC Fernandes… - Journal of Lipid …, 2024 - jlr.org
Obesity is associated with the development of local adipose tissue (AT) and systemic
inflammation. Most adipokines are upregulated with obesity and have pro-inflammatory …

Apolipoprotein M: new connections with diet, adipose tissue and metabolic syndrome

G Tavernier, S Caspar-Bauguil… - Current opinion in …, 2020 - journals.lww.com
The adipose tissue is an endocrine organ responsible for obesity-related comorbidities.
Obesity and dieting impact the adipose tissue secretory profile. The recent demonstration of …

The effects and possible mechanism of action of apolipoprotein M on the growth of breast cancer cells

Y Zhou, S Yao, M Yu, J Wei, Q Fang, N Xu… - Molecular biology …, 2022 - Springer
Background To investigate the effects and mechanism of action of apolipoprotein M (ApoM)
on the growth of breast cancer (BC) cells. Methods and results Bioinformatics, cell …

Effect of fasting and feeding on apolipoprotein AI kinetics in preβ1-HDL, α-HDL, and triglyceride-rich lipoproteins

M Chétiveaux, M Croyal, K Ouguerram, F Fall, L Flet… - Scientific Reports, 2020 - nature.com
The aim of this study was to compare the kinetics of apolipoprotein (apo) AI during fed and
fasted states in humans, and to determine to what extent the intestine contributes to apoA-I …