Monoclonal antibody self-association, cluster formation, and rheology at high concentrations

WG Lilyestrom, S Yadav, SJ Shire… - The Journal of Physical …, 2013 - ACS Publications
The rheological properties of macromolecular and colloidal suspensions are dependent on
the thermodynamic and kinetic parameters that define viscous flow, and remain an active …

Experimental and modeling study of breakage and restructuring of open and dense colloidal aggregates

YM Harshe, M Lattuada, M Soos - Langmuir, 2011 - ACS Publications
In this work we present experimental and simulation analysis of the breakage and
restructuring of colloidal aggregates in dilute conditions under shear. In order to cover a …

Breakage rate of colloidal aggregates in shear flow through Stokesian dynamics

YM Harshe, M Lattuada - Langmuir, 2012 - ACS Publications
We study the first breakage event of colloidal aggregates exposed to shear flow by detailed
numerical analysis of the process. We have formulated a model, which uses Stokesian …

Breakup of finite-size colloidal aggregates in turbulent flow investigated by three-dimensional (3D) particle tracking velocimetry

D Saha, MU Babler, M Holzner, M Soos, B Lüthi… - Langmuir, 2016 - ACS Publications
Aggregates grown in mild shear flow are released, one at a time, into homogeneous
isotropic turbulence, where their motion and intermittent breakup is recorded by three …

Numerical simulations of aggregate breakup in bounded and unbounded turbulent flows

MU Babler, L Biferale, L Brandt, U Feudel… - Journal of Fluid …, 2015 - cambridge.org
Breakup of small aggregates in fully developed turbulence is studied by means of direct
numerical simulations in a series of typical bounded and unbounded flow configurations …

Stability characteristics of nanoparticles in a laminar linear shear flow in the presence of DLVO and non-DLVO forces

V Bal - Langmuir, 2019 - ACS Publications
Stability characteristics of colloids in a laminar flow have been studied by solving the Fokker–
Plank equation for the pair probability density function. This was done by simultaneously …

Experimental determination of maximum effective hydrodynamic stress in multiphase flow using shear sensitive aggregates

TK Villiger, M Morbidelli, M Soos - AIChE Journal, 2015 - Wiley Online Library
Maximum effective hydrodynamic stress,, responsible for the breakup of aggregates with
size comparable to Kolmogorov eddies, was experimentally determined in an aerated stirred …

Experimental characterization of breakage rate of colloidal aggregates in axisymmetric extensional flow

D Saha, M Soos, B Lüthi, M Holzner, A Liberzon… - Langmuir, 2014 - ACS Publications
Aggregates prepared under fully destabilized conditions by the action of Brownian motion
were exposed to an extensional flow generated at the entrance of a sudden contraction. Two …

Universal breakup of colloidal clusters in simple shear flow

YM Harshe, M Lattuada - The Journal of Physical Chemistry B, 2016 - ACS Publications
We have studied the long-term dynamics of shear-induced breakage of individual colloidal
clusters, covering a wide range of fractal dimensions, using Stokesian dynamics. We found …

Accurate and fast numerical algorithms for tracking particle size distributions during nanoparticle aggregation and dissolution

AL Dale, GV Lowry, EA Casman - Environmental Science: Nano, 2017 - pubs.rsc.org
Particle size affects the toxicity and environmental fate of engineered nanoparticles (NPs).
Although size effects have been widely studied in the experimental NP fate and toxicity …