Monoclonal antibody self-association, cluster formation, and rheology at high concentrations
WG Lilyestrom, S Yadav, SJ Shire… - The Journal of Physical …, 2013 - ACS Publications
The rheological properties of macromolecular and colloidal suspensions are dependent on
the thermodynamic and kinetic parameters that define viscous flow, and remain an active …
the thermodynamic and kinetic parameters that define viscous flow, and remain an active …
Experimental and modeling study of breakage and restructuring of open and dense colloidal aggregates
In this work we present experimental and simulation analysis of the breakage and
restructuring of colloidal aggregates in dilute conditions under shear. In order to cover a …
restructuring of colloidal aggregates in dilute conditions under shear. In order to cover a …
Breakage rate of colloidal aggregates in shear flow through Stokesian dynamics
YM Harshe, M Lattuada - Langmuir, 2012 - ACS Publications
We study the first breakage event of colloidal aggregates exposed to shear flow by detailed
numerical analysis of the process. We have formulated a model, which uses Stokesian …
numerical analysis of the process. We have formulated a model, which uses Stokesian …
Breakup of finite-size colloidal aggregates in turbulent flow investigated by three-dimensional (3D) particle tracking velocimetry
Aggregates grown in mild shear flow are released, one at a time, into homogeneous
isotropic turbulence, where their motion and intermittent breakup is recorded by three …
isotropic turbulence, where their motion and intermittent breakup is recorded by three …
Numerical simulations of aggregate breakup in bounded and unbounded turbulent flows
Breakup of small aggregates in fully developed turbulence is studied by means of direct
numerical simulations in a series of typical bounded and unbounded flow configurations …
numerical simulations in a series of typical bounded and unbounded flow configurations …
Stability characteristics of nanoparticles in a laminar linear shear flow in the presence of DLVO and non-DLVO forces
V Bal - Langmuir, 2019 - ACS Publications
Stability characteristics of colloids in a laminar flow have been studied by solving the Fokker–
Plank equation for the pair probability density function. This was done by simultaneously …
Plank equation for the pair probability density function. This was done by simultaneously …
Experimental determination of maximum effective hydrodynamic stress in multiphase flow using shear sensitive aggregates
TK Villiger, M Morbidelli, M Soos - AIChE Journal, 2015 - Wiley Online Library
Maximum effective hydrodynamic stress,, responsible for the breakup of aggregates with
size comparable to Kolmogorov eddies, was experimentally determined in an aerated stirred …
size comparable to Kolmogorov eddies, was experimentally determined in an aerated stirred …
Experimental characterization of breakage rate of colloidal aggregates in axisymmetric extensional flow
Aggregates prepared under fully destabilized conditions by the action of Brownian motion
were exposed to an extensional flow generated at the entrance of a sudden contraction. Two …
were exposed to an extensional flow generated at the entrance of a sudden contraction. Two …
Universal breakup of colloidal clusters in simple shear flow
YM Harshe, M Lattuada - The Journal of Physical Chemistry B, 2016 - ACS Publications
We have studied the long-term dynamics of shear-induced breakage of individual colloidal
clusters, covering a wide range of fractal dimensions, using Stokesian dynamics. We found …
clusters, covering a wide range of fractal dimensions, using Stokesian dynamics. We found …
Accurate and fast numerical algorithms for tracking particle size distributions during nanoparticle aggregation and dissolution
Particle size affects the toxicity and environmental fate of engineered nanoparticles (NPs).
Although size effects have been widely studied in the experimental NP fate and toxicity …
Although size effects have been widely studied in the experimental NP fate and toxicity …