Cells of the innate immune system, notably macrophages, neutrophils and dendritic cells,
perform essential antimicrobial and homeostatic functions. These functions rely on the …

Macropinocytosis is a unique pathway of endocytosis characterised by the nonspecific
internalisation of large amounts of extracellular fluid, solutes and membrane in large …

Abstract mRNA vaccines have become a versatile technology for the prevention of infectious
diseases and the treatment of cancers. In the vaccination process, mRNA formulation and …

Macropinocytosis is defined as an actin-dependent but coat-and dynamin-independent
endocytic uptake process, which generates large intracellular vesicles (macropinosomes) …

mRNA vaccines have been revolutionary in combating the COVID-19 pandemic in the past
two years. They have also become a versatile tool for the prevention of infectious diseases …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. Although previous
studies have demonstrated that SLE is related to the imbalance of cells in the immune …

Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

Macropinocytosis has received increasing attention in recent years for its various roles in
nutrient acquisition, immune surveillance, and virus and cancer pathologies. In most cases …

Endocytosis mechanisms are one of the methods that cells use to interact with their
environments. Endocytosis mechanisms vary from the clathrin-mediated endocytosis to the …

Objective: Macrophages are immune cells, capable to remodel the extracellular matrix,
which can harbor extracellular DNA incorporated into neutrophil extracellular traps (NETs) …