Metal-catalyzed azide-alkyne “click” reactions: Mechanistic overview and recent trends

C Wang, D Ikhlef, S Kahlal, JY Saillard… - Coordination Chemistry …, 2016 - Elsevier
This review is focused on the mechanistic aspects and recent trends of the metal-catalyzed
azide-alkyne cycloaddition (MAAC) so-called “click” reactions with catalysts based on …

[HTML][HTML] Advancements in the mechanistic understanding of the copper-catalyzed azide–alkyne cycloaddition

R Berg, BF Straub - Beilstein journal of organic chemistry, 2013 - beilstein-journals.org
The copper-catalyzed azide–alkyne cycloaddition (CuAAC) is one of the most broadly
applicable and easy-to-handle reactions in the arsenal of organic chemistry. However, the …

A High‐Yielding Active Template Click Reaction (AT− CuAAC) for the Synthesis of Mechanically Interlocked Nanohoops

JH May, JM Fehr, JC Lorenz… - Angewandte Chemie …, 2024 - Wiley Online Library
Mechanically interlocked molecules (MIMs) represent an exciting yet underexplored area of
research in the context of carbon nanoscience. Recently, work from our group and others …

Dicopper Cu (I) Cu (I) and Cu (I) Cu (II) complexes in copper-catalyzed azide–alkyne cycloaddition

MS Ziegler, KV Lakshmi, TD Tilley - Journal of the American …, 2017 - ACS Publications
A discrete, dicopper μ-alkynyl complex,[Cu2 (μ-η1: η1-C C (C6H4) CH3) DPFN] NTf2
(DPFN= 2, 7-bis (fluoro-di (2-pyridyl) methyl)-1, 8-naphthyridine; NTf2–= N (SO2CF3) 2–) …

Multicomponent syntheses based upon copper‐catalyzed alkyne‐azide cycloaddition

S Hassan, TJJ Mueller - Advanced Synthesis & Catalysis, 2015 - Wiley Online Library
The copper‐catalyzed alkyne‐azide cycloaddition (CuAAC) is a highly versatile,
regioselective synthesis of 1, 4‐disubstituted 1, 2, 3‐triazoles under mild reaction conditions …

Concerted cycloaddition mechanism in the CuAAC reaction catalyzed by 1, 8-naphthyridine dicopper complexes

J Héron, D Balcells - ACS Catalysis, 2022 - ACS Publications
Copper-catalyzed azide-alkyne cycloaddition (CuAAC) is one of the most versatile reactions
in the “click chemistry” toolbox, and its development has made the synthesis of 1, 4-triazole …

Multicomponent click synthesis of 1, 2, 3-triazoles from epoxides in water catalyzed by copper nanoparticles on activated carbon

F Alonso, Y Moglie, G Radivoy… - The Journal of Organic …, 2011 - ACS Publications
Copper nanoparticles on activated carbon have been found to effectively catalyze the
multicomponent synthesis of β-hydroxy-1, 2, 3-triazoles from a variety of epoxides and …

A fluxional copper acetylide cluster in CuAAC catalysis

A Makarem, R Berg, F Rominger… - Angewandte Chemie …, 2015 - Wiley Online Library
A molecularly defined copper acetylide cluster with ancillary N‐heterocyclic carbene (NHC)
ligands was prepared under acidic reaction conditions. This cluster is the first molecular …

A reusable polymer‐supported copper (I) catalyst for triazole click reaction on water: An experimental and computational study

L Bahsis, H Ben El Ayouchia, H Anane… - Applied …, 2019 - Wiley Online Library
In the search for establishing a clickable copper‐catalysed (3+ 2) Huisgen azide–alkyne
cycloaddition (CuAAC) reaction under strict conditions, in particular in terms of preventing …

Computational studies of the CuAAC reaction mechanism with diimine and phosphorus ligands for the synthesis of 1, 4-disubstituted 1, 2, 3-triazoles

MAAH Badawi, AA Khairbek, R Thomas - New Journal of Chemistry, 2023 - pubs.rsc.org
The Cu (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with diimine and
phosphorus ligands have been studied using DFT calculations at the MN12-L/Def2-SVP …