The major facilitator superfamily (MFS) is one of the largest groups of secondary active
transporters conserved from bacteria to humans. MFS proteins selectively transport a wide …

There are currently few antifungals in use which show efficacy against fungal diseases.
These antifungals mostly target specific components of fungal plasma membrane or its …

Asian cultivated rice (Oryza sativa L.) consists of two main subspecies, indica and japonica.
Indica has higher nitrate-absorption activity than japonica, but the molecular mechanisms …

It is now well-known that the enhanced expression of ATP binding cassette (ABC) and major
facilitator superfamily (MFS) proteins contribute to the development of tolerance to …

Major facilitator superfamily (MFS) is a large class of secondary active transporters widely
expressed across all life kingdoms. Although a common 12‐transmembrane helix‐bundle …

Fungal virulence mechanisms include adhesion to epithelia, morphogenesis, production of
secretory hydrolytic enzymes, and phenotype switching, all of which contribute to the …

Candida albicans is a pathogenic fungus causing vulvovaginal candidiasis (VVC). Azole
drugs, such as fluconazole, are the most common treatment for these infections. Recently …

Over-expression of the human P-glycoprotein (P-gp) in tumor cells is a classic example of an
ABC protein serving as a hindrance to effective chemotherapy. The existence of proteins …

ABC (ATP-binding cassette) and MFS (major facilitator superfamily) exporters, belonging to
two different superfamilies, are one of the most prominent contributors of multidrug …

Drug resistance mechanisms in the commensal human pathogen Candida albicans are
continually evolving. Over time, Candida species have implemented diverse strategies to …