Staphylococcus epidermidis and its dual lifestyle in skin health and infection

MM Severn, AR Horswill - Nature Reviews Microbiology, 2023 - nature.com
The coagulase-negative bacterium Staphylococcus epidermidis is a member of the human
skin microbiota. S. epidermidis is not merely a passive resident on skin but actively primes …

[HTML][HTML] The staphylococcal exopolysaccharide PIA–Biosynthesis and role in biofilm formation, colonization, and infection

HTT Nguyen, TH Nguyen, M Otto - Computational and Structural …, 2020 - Elsevier
Exopolysaccharide is a key part of the extracellular matrix that contributes to important
mechanisms of bacterial pathogenicity, most notably biofilm formation and immune evasion …

Virulence factors in coagulase-negative staphylococci

A França, V Gaio, N Lopes, LDR Melo - Pathogens, 2021 - mdpi.com
Coagulase-negative staphylococci (CoNS) have emerged as major pathogens in healthcare-
associated facilities, being S. epidermidis, S. haemolyticus and, more recently, S …

The skin microbiome: current landscape and future opportunities

P Smythe, HN Wilkinson - International journal of molecular sciences, 2023 - mdpi.com
Our skin is the largest organ of the body, serving as an important barrier against the harsh
extrinsic environment. Alongside preventing desiccation, chemical damage and …

Update on coagulase-negative staphylococci—what the clinician should know

R Michels, K Last, SL Becker, C Papan - Microorganisms, 2021 - mdpi.com
Coagulase-negative staphylococci (CoNS) are among the most frequently recovered
bacteria in routine clinical care. Their incidence has steadily increased over the past …

Discovery and engineering of the antibody response to a prominent skin commensal

D Bousbaine, KD Bauman, YE Chen, PV Lalgudi… - Nature, 2024 - nature.com
The ubiquitous skin colonist Staphylococcus epidermidis elicits a CD8+ T cell response pre-
emptively, in the absence of an infection 1. However, the scope and purpose of this …

Genome evolution and the emergence of pathogenicity in avian Escherichia coli

L Mageiros, G Méric, SC Bayliss, J Pensar… - Nature …, 2021 - nature.com
Chickens are the most common birds on Earth and colibacillosis is among the most common
diseases affecting them. This major threat to animal welfare and safe sustainable food …

Staphylococcus epidermidis : A Potential New Player in the Physiopathology of Acne?

JP Claudel, N Auffret, MT Leccia, F Poli, S Corvec… - Dermatology, 2019 - karger.com
Background: Cutibacterium acnes has been identified as one of the main triggers of acne.
However, increasing knowledge of the human skin microbiome raises questions about the …

Emergence of coagulase-negative staphylococci

K Becker, A Both, S Weißelberg… - Expert review of anti …, 2020 - Taylor & Francis
ABSTRACT Introduction: Compared to Staphylococcus aureus, coagulase-negative
staphylococci (CoNS) are characterized by a lower capacity to cause acute, live-threatened …

Host-specific evolutionary and transmission dynamics shape the functional diversification of Staphylococcus epidermidis in human skin

W Zhou, M Spoto, R Hardy, C Guan, E Fleming… - Cell, 2020 - cell.com
Metagenomic inferences of bacterial strain diversity and infectious disease transmission
studies largely assume a dominant, within-individual haplotype. We hypothesize that within …